This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

1gu2

From Proteopedia

(Difference between revisions)

Jump to: navigation, search

Revision as of 09:52, 22 March 2017

Crystal structure of oxidized cytochrome c from Methylophilus methylotrophus

Structural highlights

1gu2 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Related:	1e8e
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The crystal structures of the oxidized and reduced forms of cytochrome c" from Methylophilus methylotrophus were solved from X-ray synchrotron data to atomic resolution. The overall fold of the molecule in the two redox states is very similar and is comparable to that of the oxygen-binding protein from the purple phototrophic bacterium Rhodobacter sphaeroides. However, significant modifications occur near the haem group, in particular the detachment from axial binding of His95 observed upon reduction as well as the adoption of different conformations of some protonatable residues that form a possible proton path from the haem pocket to the protein surface. These changes are associated with the previously well characterized redox-Bohr behaviour of this protein. Furthermore they provide a model for one of the presently proposed mechanisms of proton translocation in the much more complex protein cytochrome c oxidase.

Structural evidence for a proton transfer pathway coupled with haem reduction of cytochrome c" from Methylophilus methylotrophus.,Enguita FJ, Pohl E, Turner DL, Santos H, Carrondo MA J Biol Inorg Chem. 2006 Mar;11(2):189-96. Epub 2005 Dec 10. PMID:16341897^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Enguita FJ, Pohl E, Turner DL, Santos H, Carrondo MA. Structural evidence for a proton transfer pathway coupled with haem reduction of cytochrome c" from Methylophilus methylotrophus. J Biol Inorg Chem. 2006 Mar;11(2):189-96. Epub 2005 Dec 10. PMID:16341897 doi:10.1007/s00775-005-0065-6

1 Structural highlights
2 Evolutionary Conservation
3 Publication Abstract from PubMed
4 See Also
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1gu2"

@@ Line 1: / Line 1: @@
-==CRYSTAL STRUCTURE OF OXIDIZED CYTOCHROME C'' FROM METHYLOPHILUS METHYLOTROPHUS==
+==Crystal structure of oxidized cytochrome c'' from Methylophilus methylotrophus==
 <StructureSection load='1gu2' size='340' side='right' caption='[[1gu2]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1gu2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylophilus_w3a1 Methylophilus w3a1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GU2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GU2 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1gu2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GU2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GU2 FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e8e|1e8e]]</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gu2 OCA], [http://pdbe.org/1gu2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gu2 RCSB], [http://www.ebi.ac.uk/pdbsum/1gu2 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gu2 OCA], [http://pdbe.org/1gu2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gu2 RCSB], [http://www.ebi.ac.uk/pdbsum/1gu2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gu2 ProSAT]</span></td></tr>
 </table>
 == Evolutionary Conservation ==
@@ Line 33: / Line 34: @@
 __TOC__
 </StructureSection>
-[[Category: Methylophilus w3a1]]
 [[Category: Carrondo, M A]]
 [[Category: Enguita, F J]]

1gu2

From Proteopedia

Revision as of 09:52, 22 March 2017

Crystal structure of oxidized cytochrome c from Methylophilus methylotrophus

Structural highlights

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox