1u0w

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==An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure==
==An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure==
<StructureSection load='1u0w' size='340' side='right' caption='[[1u0w]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1u0w' size='340' side='right' caption='[[1u0w]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHS2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3879 Alfalfa])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHS2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3879 Alfalfa])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naringenin-chalcone_synthase Naringenin-chalcone synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.74 2.3.1.74] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naringenin-chalcone_synthase Naringenin-chalcone synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.74 2.3.1.74] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0w OCA], [http://pdbe.org/1u0w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u0w RCSB], [http://www.ebi.ac.uk/pdbsum/1u0w PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0w OCA], [http://pdbe.org/1u0w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u0w RCSB], [http://www.ebi.ac.uk/pdbsum/1u0w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1u0w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u0/1u0w_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u0/1u0w_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Alpha-beta-alpha-beta-alpha fold]]
[[Category: Alpha-beta-alpha-beta-alpha fold]]
[[Category: Catalytic triad]]
[[Category: Catalytic triad]]
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[[Category: Chalcone synthase]]
 
[[Category: Ch]]
[[Category: Ch]]
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[[Category: Chalcone synthase]]
[[Category: Condensing enzyme]]
[[Category: Condensing enzyme]]
[[Category: Engineered resveratrol synthase]]
[[Category: Engineered resveratrol synthase]]
[[Category: Pk]]
[[Category: Pk]]
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[[Category: R]]
 
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[[Category: Stilbene synthase]]
 
[[Category: St]]
[[Category: St]]
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[[Category: Stilbene synthase]]
[[Category: Thiolase fold]]
[[Category: Thiolase fold]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Type iii polyketide synthase]]
[[Category: Type iii polyketide synthase]]

Revision as of 08:28, 21 March 2018

An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure

1u0w, resolution 2.00Å

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