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2vx1
From Proteopedia
(Difference between revisions)
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| - | == | + | |
| + | ==ephB4 kinase domain inhibitor complex== | ||
<StructureSection load='2vx1' size='340' side='right' caption='[[2vx1]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='2vx1' size='340' side='right' caption='[[2vx1]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2vx1]] is a 1 chain structure | + | <table><tr><td colspan='2'>[[2vx1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VX1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7X8:3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE'>7X8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7X8:3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE'>7X8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bba|2bba]], [[2vwu|2vwu]], [[2vwv|2vwv]], [[2vwy|2vwy]], [[2vww|2vww]], [[2vwx|2vwx]], [[2vwz|2vwz]], [[2vx0|2vx0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bba|2bba]], [[2vwu|2vwu]], [[2vwv|2vwv]], [[2vwy|2vwy]], [[2vww|2vww]], [[2vwx|2vwx]], [[2vwz|2vwz]], [[2vx0|2vx0]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx1 OCA], [http://pdbe.org/2vx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vx1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx1 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx1 OCA], [http://pdbe.org/2vx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vx1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Human]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Barratt, D]] | [[Category: Barratt, D]] | ||
| Line 43: | Line 43: | ||
[[Category: Kettle, J G]] | [[Category: Kettle, J G]] | ||
[[Category: Leach, A G]] | [[Category: Leach, A G]] | ||
| - | [[Category: | + | [[Category: McCall, E J]] |
[[Category: Read, J]] | [[Category: Read, J]] | ||
[[Category: Valentine, A L]] | [[Category: Valentine, A L]] | ||
| Line 53: | Line 53: | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Receptor tyrosine kinase]] | [[Category: Receptor tyrosine kinase]] | ||
Revision as of 08:40, 3 August 2017
ephB4 kinase domain inhibitor complex
| |||||||||||
Categories: Receptor protein-tyrosine kinase | Barratt, D | Brassington, C A | Green, I | Kettle, J G | Leach, A G | McCall, E J | Read, J | Valentine, A L | Atp-binding | Glycoprotein | Kinase | Membrane | Mutant | Nucleotide-binding | Phosphoprotein | Polymorphism | Receptor | Receptor tyrosine kinase | Transferase | Transmembrane | Tyrosine-protein kinase | Unphosphorylated
