3ixe

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==Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase==
==Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase==
<StructureSection load='3ixe' size='340' side='right' caption='[[3ixe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3ixe' size='340' side='right' caption='[[3ixe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ILK, ILK1, ILK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), LIMS2, PINCH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ILK, ILK1, ILK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), LIMS2, PINCH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ixe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ixe OCA], [http://pdbe.org/3ixe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ixe RCSB], [http://www.ebi.ac.uk/pdbsum/3ixe PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ixe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ixe OCA], [http://pdbe.org/3ixe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ixe RCSB], [http://www.ebi.ac.uk/pdbsum/3ixe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ixe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/3ixe_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/3ixe_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Chiswell, B P]]
[[Category: Chiswell, B P]]
[[Category: Stiegler, A L]]
[[Category: Stiegler, A L]]
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[[Category: Alternative splicing]]
[[Category: Ank]]
[[Category: Ank]]
[[Category: Ank repeat]]
[[Category: Ank repeat]]
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[[Category: Signaling protein-signaling protein complex]]
[[Category: Signaling protein-signaling protein complex]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Zinc]]

Revision as of 09:33, 19 December 2018

Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase

3ixe, resolution 1.90Å

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