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| - | ==Methyltransferase domain of human Bicoid-interacting protein 3 homolog (Drosophila)==
| + | #REDIRECT [[5una]] This PDB entry is obsolete and replaced by 5una |
| - | <StructureSection load='3g07' size='340' side='right' caption='[[3g07]], [[Resolution|resolution]] 2.65Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[3g07]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G07 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G07 FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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| - | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MEPCE, BCDIN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g07 OCA], [http://pdbe.org/3g07 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g07 RCSB], [http://www.ebi.ac.uk/pdbsum/3g07 PDBsum]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/MEPCE_HUMAN MEPCE_HUMAN]] S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.<ref>PMID:17643375</ref>
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| - | == Evolutionary Conservation ==
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| - | [[Image:Consurf_key_small.gif|200px|right]]
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| - | Check<jmol>
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| - | <jmolCheckbox>
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| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/3g07_consurf.spt"</scriptWhenChecked>
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| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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| - | <text>to colour the structure by Evolutionary Conservation</text>
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| - | </jmolCheckbox>
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| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g07 ConSurf].
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| - | <div style="clear:both"></div>
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Human]]
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| - | [[Category: Arrowsmith, C H]]
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| - | [[Category: Bochkarev, A]]
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| - | [[Category: Bountra, C]]
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| - | [[Category: Dombrovski, L]]
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| - | [[Category: Edwards, A M]]
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| - | [[Category: Loppnau, P]]
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| - | [[Category: McCarthy, A]]
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| - | [[Category: Min, J]]
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| - | [[Category: Park, H]]
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| - | [[Category: Plotnikov, A N]]
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| - | [[Category: Structural genomic]]
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| - | [[Category: Tempel, W]]
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| - | [[Category: Weigelt, J]]
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| - | [[Category: Wu, H]]
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| - | [[Category: Methyltransferase]]
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| - | [[Category: Phosphoprotein]]
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| - | [[Category: S-adenosyl-l-methionine]]
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| - | [[Category: Transferase]]
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