1dfj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1dfj.jpg|left|200px]]
[[Image:1dfj.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1dfj |SIZE=350|CAPTION= <scene name='initialview01'>1dfj</scene>, resolution 2.5&Aring;
+
The line below this paragraph, containing "STRUCTURE_1dfj", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1dfj| PDB=1dfj | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dfj OCA], [http://www.ebi.ac.uk/pdbsum/1dfj PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dfj RCSB]</span>
+
-
}}
+
'''RIBONUCLEASE INHIBITOR COMPLEXED WITH RIBONUCLEASE A'''
'''RIBONUCLEASE INHIBITOR COMPLEXED WITH RIBONUCLEASE A'''
Line 29: Line 26:
[[Category: Deisenhofer, J.]]
[[Category: Deisenhofer, J.]]
[[Category: Kobe, B.]]
[[Category: Kobe, B.]]
-
[[Category: complex (ribonuclease/inhibitor)]]
+
[[Category: Hydrolase]]
-
[[Category: hydrolase]]
+
[[Category: Leucine-rich repeat]]
-
[[Category: leucine-rich repeat]]
+
[[Category: Ribonuclease]]
-
[[Category: ribonuclease]]
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:47:59 2008''
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:40:42 2008''
+

Revision as of 10:48, 2 May 2008

Image:1dfj.jpg

Template:STRUCTURE 1dfj

RIBONUCLEASE INHIBITOR COMPLEXED WITH RIBONUCLEASE A


Overview

The leucine-rich repeat is a recently characterized structural motif used in molecular recognition processes as diverse as signal transduction, cell adhesion, cell development, DNA repair and RNA processing. We present here the crystal structure at 2.5 A resolution of the complex between ribonuclease A and ribonuclease inhibitor, a protein built entirely of leucine-rich repeats. The unusual non-globular structure of ribonuclease inhibitor, its solvent-exposed parallel beta-sheet and the conformational flexibility of the structure are used in the interaction; they appear to be the principal reasons for the effectiveness of leucine-rich repeats as protein-binding motifs. The structure can serve as a model for the interactions of other proteins containing leucine-rich repeats with their ligands.

About this Structure

1DFJ is a Protein complex structure of sequences from Bos taurus and Sus scrofa. Full crystallographic information is available from OCA.

Reference

A structural basis of the interactions between leucine-rich repeats and protein ligands., Kobe B, Deisenhofer J, Nature. 1995 Mar 9;374(6518):183-6. PMID:7877692 Page seeded by OCA on Fri May 2 13:47:59 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1dfj"
Personal tools