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2bel
From Proteopedia
(Difference between revisions)
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| - | == | + | |
| + | ==Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone== | ||
<StructureSection load='2bel' size='340' side='right' caption='[[2bel]], [[Resolution|resolution]] 2.11Å' scene=''> | <StructureSection load='2bel' size='340' side='right' caption='[[2bel]], [[Resolution|resolution]] 2.11Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xu7|1xu7]], [[1xu9|1xu9]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xu7|1xu7]], [[1xu9|1xu9]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bel OCA], [http://pdbe.org/2bel PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bel RCSB], [http://www.ebi.ac.uk/pdbsum/2bel PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bel OCA], [http://pdbe.org/2bel PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bel RCSB], [http://www.ebi.ac.uk/pdbsum/2bel PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bel ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/be/2bel_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/be/2bel_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 18: | Line 19: | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bel ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bel ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
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[[Category: Bray, J]] | [[Category: Bray, J]] | ||
[[Category: Debreczeni, J E]] | [[Category: Debreczeni, J E]] | ||
| - | [[Category: Delft, F | + | [[Category: Delft, F von]] |
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
[[Category: Elleby, B]] | [[Category: Elleby, B]] | ||
Revision as of 18:44, 24 January 2018
Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone
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Categories: 11-beta-hydroxysteroid dehydrogenase | Human | Abrahmsen, L | Arrowsmith, C | Bray, J | Debreczeni, J E | Delft, F von | Edwards, A | Elleby, B | Kavanagh, K | Oppermann, U | Sharma, S | Sundstrom, M | Svensson, S | Wu, X | Drug target | Glucocorticoid activation | Hormone metabolism | Inhibitor | Microsome | Nadp | Oxidoreductase | Short-chain dehydrogenase/reductase | Steroid metabolism
