1dus

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[[Image:1dus.gif|left|200px]]
[[Image:1dus.gif|left|200px]]
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{{Structure
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|PDB= 1dus |SIZE=350|CAPTION= <scene name='initialview01'>1dus</scene>, resolution 1.80&Aring;
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam05175 MTS]</span>
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{{STRUCTURE_1dus| PDB=1dus | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dus OCA], [http://www.ebi.ac.uk/pdbsum/1dus PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dus RCSB]</span>
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'''MJ0882-A hypothetical protein from M. jannaschii'''
'''MJ0882-A hypothetical protein from M. jannaschii'''
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[[Category: Kim, R.]]
[[Category: Kim, R.]]
[[Category: Kim, S H.]]
[[Category: Kim, S H.]]
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[[Category: berkeley structural genomics center]]
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[[Category: Berkeley structural genomics center]]
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[[Category: bsgc structure funded by nih]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: hypothetical protein]]
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[[Category: Hypothetical protein]]
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[[Category: methanococcus jannaschii]]
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[[Category: Methanococcus jannaschii]]
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[[Category: protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: psi]]
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[[Category: Psi]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:18:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:49:07 2008''
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Revision as of 11:18, 2 May 2008

Image:1dus.gif

Template:STRUCTURE 1dus

MJ0882-A hypothetical protein from M. jannaschii


Overview

We have determined the three-dimensional (3-D) structure of protein MJ0882, which derives from a hypothetical open reading frame in the genome of the hyperthermophile Methanococcus jannaschii. The 3-D fold of MJ0882 at 1.8 A highly resembles that of a methyltransferase, despite limited sequence similarity to any confirmed methyltransferase. The structure has an S-adenosylmethionine (AdoMet) binding pocket surrounded by motifs with similarities to those commonly found among AdoMet binding proteins. Preliminary biochemical experiments show that MJ0882 specifically binds to AdoMet, which is the essential co-factor for methyltransferases.

About this Structure

1DUS is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.

Reference

Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii., Huang L, Hung L, Odell M, Yokota H, Kim R, Kim SH, J Struct Funct Genomics. 2002;2(3):121-7. PMID:12836702 Page seeded by OCA on Fri May 2 14:18:09 2008

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