This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1dzf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1dzf.jpg|left|200px]]
[[Image:1dzf.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1dzf |SIZE=350|CAPTION= <scene name='initialview01'>1dzf</scene>, resolution 1.9&Aring;
+
The line below this paragraph, containing "STRUCTURE_1dzf", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE= YBR154C OR YBR1204 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1dzf| PDB=1dzf | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dzf OCA], [http://www.ebi.ac.uk/pdbsum/1dzf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dzf RCSB]</span>
+
-
}}
+
'''RPB5 FROM S.CEREVISIAE'''
'''RPB5 FROM S.CEREVISIAE'''
Line 30: Line 27:
[[Category: Todone, F.]]
[[Category: Todone, F.]]
[[Category: Weinzierl, R O.J.]]
[[Category: Weinzierl, R O.J.]]
-
[[Category: rna polymerase subunit]]
+
[[Category: Rna polymerase subunit]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:28:16 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:51:58 2008''
+

Revision as of 11:28, 2 May 2008

Image:1dzf.jpg

Template:STRUCTURE 1dzf

RPB5 FROM S.CEREVISIAE


Overview

Eukaryotic nuclei contain three different types of RNA polymerases (RNAPs), each consisting of 12-18 different subunits. The evolutionarily highly conserved RNAP subunit RPB5 is shared by all three enzymes and therefore represents a key structural/functional component of all eukaryotic RNAPs. Here we present the crystal structure of the RPB5 subunit from Saccharomyces cerevisiae. The bipartite structure includes a eukaryote-specific N-terminal domain and a C-terminal domain resembling the archaeal RNAP subunit H. RPB5 has been implicated in direct protein-protein contacts with transcription factor IIB, one of the components of the RNAP(II) basal transcriptional machinery, and gene-specific activator proteins, such as the hepatitis B virus transactivator protein X. The experimentally mapped regions of RPB5 involved in these interactions correspond to distinct and surface-exposed alpha-helical structures.

About this Structure

1DZF is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Crystal structure of RPB5, a universal eukaryotic RNA polymerase subunit and transcription factor interaction target., Todone F, Weinzierl RO, Brick P, Onesti S, Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6306-10. PMID:10841537 Page seeded by OCA on Fri May 2 14:28:16 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1dzf"
Personal tools