1e0g
From Proteopedia
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'''LYSM DOMAIN FROM E.COLI MLTD''' | '''LYSM DOMAIN FROM E.COLI MLTD''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1E0G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry | + | 1E0G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1e01 1e01]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E0G OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Bateman, A.]] | [[Category: Bateman, A.]] | ||
[[Category: Bycroft, M.]] | [[Category: Bycroft, M.]] | ||
| - | [[Category: | + | [[Category: Cell wall]] |
| - | [[Category: | + | [[Category: Glycosidase]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| - | [[Category: | + | [[Category: Lipoprotein]] |
| - | [[Category: | + | [[Category: Multigene family]] |
| - | [[Category: | + | [[Category: Outer membrane]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:30:21 2008'' | |
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Revision as of 11:30, 2 May 2008
LYSM DOMAIN FROM E.COLI MLTD
Overview
The LysM domain is a widespread protein module. It was originally identified in enzymes that degrade bacterial cell walls but is also present in many other bacterial proteins. Several proteins that contain the domain, such as Staphylococcal IgG binding proteins and Escherichia coli intimin, are involved in bacterial pathogenesis. LysM domains are also found in some eukaryotic proteins, apparently as a result of horizontal gene transfer from bacteria. The available evidence suggests that the LysM domain is a general peptidoglycan-binding module. We have determined the structure of this domain from E. coli membrane-bound lytic murein transglycosylase D. The LysM domain has a betaalphaalphabeta secondary structure with the two helices packing onto the same side of an anti- parallel beta sheet. The structure shows no similarity to other bacterial cell surface domains. A potential binding site in a shallow groove on surface of the protein has been identified.
About this Structure
1E0G is a Single protein structure of sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1e01. Full crystallographic information is available from OCA.
Reference
The structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD)., Bateman A, Bycroft M, J Mol Biol. 2000 Jun 16;299(4):1113-9. PMID:10843862 Page seeded by OCA on Fri May 2 14:30:21 2008
