1e31

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1e31.gif|left|200px]]
[[Image:1e31.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1e31 |SIZE=350|CAPTION= <scene name='initialview01'>1e31</scene>, resolution 2.71&Aring;
+
The line below this paragraph, containing "STRUCTURE_1e31", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1e31| PDB=1e31 | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e31 OCA], [http://www.ebi.ac.uk/pdbsum/1e31 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1e31 RCSB]</span>
+
-
}}
+
'''SURVIVIN DIMER H. SAPIENS'''
'''SURVIVIN DIMER H. SAPIENS'''
Line 29: Line 26:
[[Category: Margolis, R.]]
[[Category: Margolis, R.]]
[[Category: Skoufias, D.]]
[[Category: Skoufias, D.]]
-
[[Category: apotosis]]
+
[[Category: Apotosis]]
-
[[Category: iap]]
+
[[Category: Iap]]
-
[[Category: zinc finger]]
+
[[Category: Zinc finger]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:35:49 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:54:03 2008''
+

Revision as of 11:35, 2 May 2008

Image:1e31.gif

Template:STRUCTURE 1e31

SURVIVIN DIMER H. SAPIENS


Overview

Survivin is a mitotic spindle-associated protein involved in linking mitotic spindle function to activation of apoptosis in mammalian cells. The structure of the full-length human survivin has been determined by X-ray crystallography to 2.7 A. Strikingly, the structure forms a very unusual bow tie-shaped dimer. It does not dimerize through a C-terminal coiled-coil, contrary to sequence analysis prediction. The C-terminal helices contain hydrophobic clusters with the potential for protein-protein interactions. The unusual shape and dimensions of survivin suggest it serves an adaptor function through its alpha-helical extensions.

About this Structure

1E31 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions., Chantalat L, Skoufias DA, Kleman JP, Jung B, Dideberg O, Margolis RL, Mol Cell. 2000 Jul;6(1):183-9. PMID:10949039 Page seeded by OCA on Fri May 2 14:35:49 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1e31"
Personal tools