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1uto

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==TRYPSIN SPECIFICITY AS ELUCIDATED BY LIE CALCULATIONS, X-RAY STRUCTURES AND ASSOCIATION CONSTANT MEASUREMENTS==
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==Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements==
<StructureSection load='1uto' size='340' side='right' caption='[[1uto]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
<StructureSection load='1uto' size='340' side='right' caption='[[1uto]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aq7|1aq7]], [[1auj|1auj]], [[1az8|1az8]], [[1bju|1bju]], [[1bjv|1bjv]], [[1btp|1btp]], [[1btw|1btw]], [[1btx|1btx]], [[1bty|1bty]], [[1btz|1btz]], [[1c1n|1c1n]], [[1c1o|1c1o]], [[1c1p|1c1p]], [[1c1q|1c1q]], [[1c1r|1c1r]], [[1c1s|1c1s]], [[1c1t|1c1t]], [[1c2d|1c2d]], [[1c2e|1c2e]], [[1c2f|1c2f]], [[1c2g|1c2g]], [[1c2h|1c2h]], [[1c2i|1c2i]], [[1c2j|1c2j]], [[1c2k|1c2k]], [[1c2l|1c2l]], [[1c2m|1c2m]], [[1c5p|1c5p]], [[1c5q|1c5q]], [[1c5r|1c5r]], [[1c5s|1c5s]], [[1c5t|1c5t]], [[1c5u|1c5u]], [[1c5v|1c5v]], [[1c9t|1c9t]], [[1ce5|1ce5]], [[1cu7|1cu7]], [[1cu8|1cu8]], [[1cu9|1cu9]], [[1d6r|1d6r]], [[1eb2|1eb2]], [[1ejm|1ejm]], [[1ezx|1ezx]], [[1f0t|1f0t]], [[1f0u|1f0u]], [[1f2s|1f2s]], [[1g36|1g36]], [[1g3b|1g3b]], [[1g3c|1g3c]], [[1g3d|1g3d]], [[1g3e|1g3e]], [[1g9i|1g9i]], [[1gbt|1gbt]], [[1ghz|1ghz]], [[1gi0|1gi0]], [[1gi1|1gi1]], [[1gi2|1gi2]], [[1gi3|1gi3]], [[1gi4|1gi4]], [[1gi5|1gi5]], [[1gi6|1gi6]], [[1gj6|1gj6]], [[1hj9|1hj9]], [[1j8a|1j8a]], [[1jir|1jir]], [[1jrs|1jrs]], [[1jrt|1jrt]], [[1k1i|1k1i]], [[1k1j|1k1j]], [[1k1l|1k1l]], [[1k1m|1k1m]], [[1k1n|1k1n]], [[1k1o|1k1o]], [[1k1p|1k1p]], [[1lqe|1lqe]], [[1max|1max]], [[1may|1may]], [[1mts|1mts]], [[1mtu|1mtu]], [[1mtv|1mtv]], [[1mtw|1mtw]], [[1n6x|1n6x]], [[1n6y|1n6y]], [[1nc6|1nc6]], [[1ntp|1ntp]], [[1o2h|1o2h]], [[1o2i|1o2i]], [[1o2j|1o2j]], [[1o2k|1o2k]], [[1o2l|1o2l]], [[1o2m|1o2m]], [[1o2n|1o2n]], [[1o2o|1o2o]], [[1o2p|1o2p]], [[1o2q|1o2q]], [[1o2r|1o2r]], [[1o2s|1o2s]], [[1o2t|1o2t]], [[1o2u|1o2u]], [[1o2v|1o2v]], [[1o2w|1o2w]], [[1o2x|1o2x]], [[1o2y|1o2y]], [[1o2z|1o2z]], [[1o30|1o30]], [[1o31|1o31]], [[1o32|1o32]], [[1o33|1o33]], [[1o34|1o34]], [[1o35|1o35]], [[1o36|1o36]], [[1o37|1o37]], [[1o38|1o38]], [[1o39|1o39]], [[1o3a|1o3a]], [[1o3b|1o3b]], [[1o3c|1o3c]], [[1o3d|1o3d]], [[1o3e|1o3e]], [[1o3f|1o3f]], [[1o3g|1o3g]], [[1o3h|1o3h]], [[1o3i|1o3i]], [[1o3j|1o3j]], [[1o3k|1o3k]], [[1o3l|1o3l]], [[1o3m|1o3m]], [[1o3n|1o3n]], [[1o3o|1o3o]], [[1oph|1oph]], [[1oyq|1oyq]], [[1ppc|1ppc]], [[1ppe|1ppe]], [[1pph|1pph]], [[1qa0|1qa0]], [[1qb1|1qb1]], [[1qb6|1qb6]], [[1qb9|1qb9]], [[1qbn|1qbn]], [[1qbo|1qbo]], [[1qcp|1qcp]], [[1ql7|1ql7]], [[1ql8|1ql8]], [[1sbw|1sbw]], [[1sfi|1sfi]], [[1smf|1smf]], [[1tab|1tab]], [[1taw|1taw]], [[1tgb|1tgb]], [[1tgc|1tgc]], [[1tgn|1tgn]], [[1tgs|1tgs]], [[1tgt|1tgt]], [[1tio|1tio]], [[1tld|1tld]], [[1tng|1tng]], [[1tnh|1tnh]], [[1tni|1tni]], [[1tnj|1tnj]], [[1tnk|1tnk]], [[1tnl|1tnl]], [[1tpa|1tpa]], [[1tpo|1tpo]], [[1tpp|1tpp]], [[1tps|1tps]], [[1tyn|1tyn]], [[1utn|1utn]], [[1xuf|1xuf]], [[1xug|1xug]], [[1xuh|1xuh]], [[1xui|1xui]], [[1xuj|1xuj]], [[1xuk|1xuk]], [[1yyy|1yyy]], [[1zzz|1zzz]], [[2btc|2btc]], [[2bza|2bza]], [[2ptc|2ptc]], [[2ptn|2ptn]], [[2tga|2tga]], [[2tgd|2tgd]], [[2tgp|2tgp]], [[2tgt|2tgt]], [[2tio|2tio]], [[2tld|2tld]], [[2tpi|2tpi]], [[3btd|3btd]], [[3bte|3bte]], [[3btf|3btf]], [[3btg|3btg]], [[3bth|3bth]], [[3btk|3btk]], [[3btm|3btm]], [[3btq|3btq]], [[3btt|3btt]], [[3btw|3btw]], [[3ptb|3ptb]], [[3ptn|3ptn]], [[3tpi|3tpi]], [[4tpi|4tpi]], [[5ptp|5ptp]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aq7|1aq7]], [[1auj|1auj]], [[1az8|1az8]], [[1bju|1bju]], [[1bjv|1bjv]], [[1btp|1btp]], [[1btw|1btw]], [[1btx|1btx]], [[1bty|1bty]], [[1btz|1btz]], [[1c1n|1c1n]], [[1c1o|1c1o]], [[1c1p|1c1p]], [[1c1q|1c1q]], [[1c1r|1c1r]], [[1c1s|1c1s]], [[1c1t|1c1t]], [[1c2d|1c2d]], [[1c2e|1c2e]], [[1c2f|1c2f]], [[1c2g|1c2g]], [[1c2h|1c2h]], [[1c2i|1c2i]], [[1c2j|1c2j]], [[1c2k|1c2k]], [[1c2l|1c2l]], [[1c2m|1c2m]], [[1c5p|1c5p]], [[1c5q|1c5q]], [[1c5r|1c5r]], [[1c5s|1c5s]], [[1c5t|1c5t]], [[1c5u|1c5u]], [[1c5v|1c5v]], [[1c9t|1c9t]], [[1ce5|1ce5]], [[1cu7|1cu7]], [[1cu8|1cu8]], [[1cu9|1cu9]], [[1d6r|1d6r]], [[1eb2|1eb2]], [[1ejm|1ejm]], [[1ezx|1ezx]], [[1f0t|1f0t]], [[1f0u|1f0u]], [[1f2s|1f2s]], [[1g36|1g36]], [[1g3b|1g3b]], [[1g3c|1g3c]], [[1g3d|1g3d]], [[1g3e|1g3e]], [[1g9i|1g9i]], [[1gbt|1gbt]], [[1ghz|1ghz]], [[1gi0|1gi0]], [[1gi1|1gi1]], [[1gi2|1gi2]], [[1gi3|1gi3]], [[1gi4|1gi4]], [[1gi5|1gi5]], [[1gi6|1gi6]], [[1gj6|1gj6]], [[1hj9|1hj9]], [[1j8a|1j8a]], [[1jir|1jir]], [[1jrs|1jrs]], [[1jrt|1jrt]], [[1k1i|1k1i]], [[1k1j|1k1j]], [[1k1l|1k1l]], [[1k1m|1k1m]], [[1k1n|1k1n]], [[1k1o|1k1o]], [[1k1p|1k1p]], [[1lqe|1lqe]], [[1max|1max]], [[1may|1may]], [[1mts|1mts]], [[1mtu|1mtu]], [[1mtv|1mtv]], [[1mtw|1mtw]], [[1n6x|1n6x]], [[1n6y|1n6y]], [[1nc6|1nc6]], [[1ntp|1ntp]], [[1o2h|1o2h]], [[1o2i|1o2i]], [[1o2j|1o2j]], [[1o2k|1o2k]], [[1o2l|1o2l]], [[1o2m|1o2m]], [[1o2n|1o2n]], [[1o2o|1o2o]], [[1o2p|1o2p]], [[1o2q|1o2q]], [[1o2r|1o2r]], [[1o2s|1o2s]], [[1o2t|1o2t]], [[1o2u|1o2u]], [[1o2v|1o2v]], [[1o2w|1o2w]], [[1o2x|1o2x]], [[1o2y|1o2y]], [[1o2z|1o2z]], [[1o30|1o30]], [[1o31|1o31]], [[1o32|1o32]], [[1o33|1o33]], [[1o34|1o34]], [[1o35|1o35]], [[1o36|1o36]], [[1o37|1o37]], [[1o38|1o38]], [[1o39|1o39]], [[1o3a|1o3a]], [[1o3b|1o3b]], [[1o3c|1o3c]], [[1o3d|1o3d]], [[1o3e|1o3e]], [[1o3f|1o3f]], [[1o3g|1o3g]], [[1o3h|1o3h]], [[1o3i|1o3i]], [[1o3j|1o3j]], [[1o3k|1o3k]], [[1o3l|1o3l]], [[1o3m|1o3m]], [[1o3n|1o3n]], [[1o3o|1o3o]], [[1oph|1oph]], [[1oyq|1oyq]], [[1ppc|1ppc]], [[1ppe|1ppe]], [[1pph|1pph]], [[1qa0|1qa0]], [[1qb1|1qb1]], [[1qb6|1qb6]], [[1qb9|1qb9]], [[1qbn|1qbn]], [[1qbo|1qbo]], [[1qcp|1qcp]], [[1ql7|1ql7]], [[1ql8|1ql8]], [[1sbw|1sbw]], [[1sfi|1sfi]], [[1smf|1smf]], [[1tab|1tab]], [[1taw|1taw]], [[1tgb|1tgb]], [[1tgc|1tgc]], [[1tgn|1tgn]], [[1tgs|1tgs]], [[1tgt|1tgt]], [[1tio|1tio]], [[1tld|1tld]], [[1tng|1tng]], [[1tnh|1tnh]], [[1tni|1tni]], [[1tnj|1tnj]], [[1tnk|1tnk]], [[1tnl|1tnl]], [[1tpa|1tpa]], [[1tpo|1tpo]], [[1tpp|1tpp]], [[1tps|1tps]], [[1tyn|1tyn]], [[1utn|1utn]], [[1xuf|1xuf]], [[1xug|1xug]], [[1xuh|1xuh]], [[1xui|1xui]], [[1xuj|1xuj]], [[1xuk|1xuk]], [[1yyy|1yyy]], [[1zzz|1zzz]], [[2btc|2btc]], [[2bza|2bza]], [[2ptc|2ptc]], [[2ptn|2ptn]], [[2tga|2tga]], [[2tgd|2tgd]], [[2tgp|2tgp]], [[2tgt|2tgt]], [[2tio|2tio]], [[2tld|2tld]], [[2tpi|2tpi]], [[3btd|3btd]], [[3bte|3bte]], [[3btf|3btf]], [[3btg|3btg]], [[3bth|3bth]], [[3btk|3btk]], [[3btm|3btm]], [[3btq|3btq]], [[3btt|3btt]], [[3btw|3btw]], [[3ptb|3ptb]], [[3ptn|3ptn]], [[3tpi|3tpi]], [[4tpi|4tpi]], [[5ptp|5ptp]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uto OCA], [http://pdbe.org/1uto PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uto RCSB], [http://www.ebi.ac.uk/pdbsum/1uto PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uto OCA], [http://pdbe.org/1uto PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uto RCSB], [http://www.ebi.ac.uk/pdbsum/1uto PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uto ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ut/1uto_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ut/1uto_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>

Revision as of 07:49, 28 March 2018

Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements

1uto, resolution 1.15Å

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