1gs3

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==HIGH RESOLUTION CRYSTAL STRUCTURE OF PI DELTA-5-3-KETOSTEROID ISOMERASE MUTANTS Y30F/Y55F/Y115F/ D38N (Y32F/Y57F/Y119F/D40N, PI NUMBERING)COMPLEXED WITH EQUILENIN AT 2.1 A RESOLUTION==
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==High resolution crystal structure of PI delta-5-3-Ketosteroid Isomerase mutants Y30F/Y55F/Y115F/D38N (Y32F/Y57F/Y119F/D40N, PI numbering)complexed with equilenin at 2.1 A resolution==
<StructureSection load='1gs3' size='340' side='right' caption='[[1gs3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1gs3' size='340' side='right' caption='[[1gs3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1c7h|1c7h]], [[1dmm|1dmm]], [[1dmn|1dmn]], [[1dmq|1dmq]], [[1e3n|1e3n]], [[1e3r|1e3r]], [[1e3v|1e3v]], [[1e97|1e97]], [[1ea2|1ea2]], [[1opy|1opy]], [[4tsu|4tsu]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1c7h|1c7h]], [[1dmm|1dmm]], [[1dmn|1dmn]], [[1dmq|1dmq]], [[1e3n|1e3n]], [[1e3r|1e3r]], [[1e3v|1e3v]], [[1e97|1e97]], [[1ea2|1ea2]], [[1opy|1opy]], [[4tsu|4tsu]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Steroid_Delta-isomerase Steroid Delta-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.1 5.3.3.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Steroid_Delta-isomerase Steroid Delta-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.1 5.3.3.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs3 OCA], [http://pdbe.org/1gs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gs3 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs3 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs3 OCA], [http://pdbe.org/1gs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gs3 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gs3 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/1gs3_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/1gs3_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gs3 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gs3 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
 
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*[[Ketosteroid Isomerase|Ketosteroid Isomerase]]
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 06:45, 3 January 2018

High resolution crystal structure of PI delta-5-3-Ketosteroid Isomerase mutants Y30F/Y55F/Y115F/D38N (Y32F/Y57F/Y119F/D40N, PI numbering)complexed with equilenin at 2.1 A resolution

1gs3, resolution 2.10Å

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