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Elongation factor

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Line 40: Line 40:
**[[1b23]] - TaEF + Cys-tRNA<BR />
**[[1b23]] - TaEF + Cys-tRNA<BR />
**[[1ls2]] – yEF + Phe-tRNA – yeast – Cryo EM<BR />
**[[1ls2]] – yEF + Phe-tRNA – yeast – Cryo EM<BR />
-
**[[3agj]] – ApEF + plethora protein – ''Aeropyrum pernix''<br />
+
**[[3wxm]] – ApEF + plethora protein – ''Aeropyrum pernix''<br />
**[[4h9g]], [[4lbv]], [[4lbw]], [[4lby]], [[4lbz]], [[4lc0]] – TtEF – ''Thermus thermophilus''<br />
**[[4h9g]], [[4lbv]], [[4lbw]], [[4lby]], [[4lbz]], [[4lc0]] – TtEF – ''Thermus thermophilus''<br />
**[[4j0q]] – EF – ''Pseudomonas putida''<br />
**[[4j0q]] – EF – ''Pseudomonas putida''<br />
Line 47: Line 47:
**[[1ob2]] - yEF + Phe-tRNA + antibiotic<BR />
**[[1ob2]] - yEF + Phe-tRNA + antibiotic<BR />
-
**[[4abr]] - TtEF + antibiotic in 30S ribosome<BR />
+
**[[4v8q]] - TtEF + antibiotic in 30S ribosome<BR />
**[[1ha3]] - TtEF + antibiotic + GDP<BR />
**[[1ha3]] - TtEF + antibiotic + GDP<BR />
**[[2c77]], [[2c78]] - TtEF + antibiotic + GTP analog<br />
**[[2c77]], [[2c78]] - TtEF + antibiotic + GTP analog<br />
-
**[[3fic]], [[3fic]] – TtEF + antibiotic in 70S ribosome – Cryo EM<BR />
+
**[[4v68]] – TtEF + antibiotic in 70S ribosome – Cryo EM<BR />
**[[2bvn]] - EcEF + GDP<BR />NP + antibiotic<BR />
**[[2bvn]] - EcEF + GDP<BR />NP + antibiotic<BR />
**[[1d8t]], [[2hcj]], [[2hdn]], [[3u6b]], [[3u6k]], [[4g5g]] – EcEF + antibiotic
**[[1d8t]], [[2hcj]], [[2hdn]], [[3u6b]], [[3u6k]], [[4g5g]] – EcEF + antibiotic
Line 67: Line 67:
**[[3vmf]] – ApEF + translation termination factor<br />
**[[3vmf]] – ApEF + translation termination factor<br />
-
**[[3wxm]] – ApEF + protein pelota homolog<br />
 
**[[3wy9]] – PhEF + L12 <br />
**[[3wy9]] – PhEF + L12 <br />
**[[4p3y]] – EcEF + thiol:disulfide interchange protein <br />
**[[4p3y]] – EcEF + thiol:disulfide interchange protein <br />
Line 88: Line 87:
**[[3eq3]], [[3eq4]] – EcEF in 80S ribosome – Cryo EM<BR />
**[[3eq3]], [[3eq4]] – EcEF in 80S ribosome – Cryo EM<BR />
-
**[[3izv]], [[3izw]], [[3fih]] - EcEF in 30S ribosome – Cryo EM<BR />
+
**[[4v6l]], [[4v6k]], [[4v69]] - EcEF in 30S ribosome – Cryo EM<BR />
**[[1zc8]], [[3dwu]] – TtEF in 70S ribosome – Cryo EM<BR />
**[[1zc8]], [[3dwu]] – TtEF in 70S ribosome – Cryo EM<BR />
-
**[[2wrn]], [[2wrq]], [[2xqd]], [[2y0u]], [[2y0w]], [[2y0y]], [[2y10]], [[2y12]], [[2y14]], [[2y16]], [[2y18]] - TtEF in 70S ribosome
+
**[[4v5g]], [[4v5l]], [[4v5p]], [[4v5q]], [[4v5r]], [[4v5s]] - TtEF in 70S ribosome
*EF-SII
*EF-SII
Line 113: Line 112:
**[[4m1k]], [[4myt]], [[4myu]] – TtEF (mutant)<br />
**[[4m1k]], [[4myt]], [[4myu]] – TtEF (mutant)<br />
**[[1pn6]], [[3izp]] – TtEF – Cryo EM<BR />
**[[1pn6]], [[3izp]] – TtEF – Cryo EM<BR />
-
**[[4b8f]], [[4b8h]] – TtEF in 70S ribosome <BR />
+
**[[4v8u]] – TtEF in 70S ribosome <BR />
-
**[[4juw]], [[4kbt]], [[4kbv]], [[4kcy]], [[4kd0]], [[4kd8]], [[4kda]], [[4kdg]], [[4kdj]], [[4btc]] – TtEF in 30S ribosome <BR />
+
**[[4v9h]], [[4v9j]], [[4v9k]], [[4v9l]], [[4v9m]], [[4v90]] – TtEF in 30S ribosome <BR />
-
**[[4kiy]], [[4kj0]], [[4kj2]], [[4kj4]], [[4kj6]], [[4kj8]], [[4kja]], [[4kjc]] – EcEF in 30S ribosome <BR />
+
**[[4v9o]], [[4v9p]] – EcEF in 30S ribosome <BR />
-
**[[3j5n]] – EcEF in 30S ribosome – Cryo-EM<BR />
+
**[[4v9b]] – EcEF in 30S ribosome – Cryo-EM<BR />
-
**[[3j5x]] – EcEF in 30S ribosome + antibiotics – Cryo-EM<BR />
+
**[[4v9d]] – EcEF in 30S ribosome + antibiotics – Cryo-EM<BR />
**[[1fnm]], [[2bm0]], [[2bm1]] – TtEF (mutant) <BR />
**[[1fnm]], [[2bm0]], [[2bm1]] – TtEF (mutant) <BR />
**[[2bcw]] – TtEF + L11 + L7/L12 <br />
**[[2bcw]] – TtEF + L11 + L7/L12 <br />
Line 125: Line 124:
**[[2j7k]] - TtEF (mutant) + GDP analog<br />
**[[2j7k]] - TtEF (mutant) + GDP analog<br />
**[[2om7]], [[2wri]], [[2wrk]] – TtEF in 70S ribosome – Cryo EM<BR />
**[[2om7]], [[2wri]], [[2wrk]] – TtEF in 70S ribosome – Cryo EM<BR />
-
**[[2xsy]], [[2xuy]] - TtEF in 70S ribosome<BR />
+
**[[4v5m]], [[4v5n]] - TtEF in 70S ribosome<BR />
**[[1dar]], [[2efg]] – TtEF + GDP<BR />
**[[1dar]], [[2efg]] – TtEF + GDP<BR />
**[[1jqm]], [[1jqs]] – EcEF + L11 – Cryo EM<BR />
**[[1jqm]], [[1jqs]] – EcEF + L11 – Cryo EM<BR />
-
**[[1zn0]], [[2rdo]], [[3j0e]], [[3j18]] – EcEF in 30S ribosome – Cryo-EM<BR />
+
**[[1zn0]], [[2rdo]], [[3j0e]], [[4v6t]] – EcEF in 30S ribosome – Cryo-EM<BR />
**[[4fn5]] – PaEF - ''Pseudomonas aeruginosa''<br />
**[[4fn5]] – PaEF - ''Pseudomonas aeruginosa''<br />
Line 146: Line 145:
**[[1ueb]] – TtEF<BR />
**[[1ueb]] – TtEF<BR />
-
**[[3huw]], [[3huy]] – TtEF in 70S ribosome<BR />
+
**[[4v6a]] – TtEF in 70S ribosome<BR />
**[[3oyy]] – PaEF <BR />
**[[3oyy]] – PaEF <BR />
**[[3tre]] – EF – ''Coxiella burnetii''<br />
**[[3tre]] – EF – ''Coxiella burnetii''<br />

Revision as of 10:54, 16 November 2016

Structure of EF-Tu (cyan and magenta) with EF-Ts (green and yellow) (PDB entry 1efu)

Drag the structure with the mouse to rotate

3D structures of elongation factor

Updated on 16-November-2016

References

  1. ↑ Takeshita D, Tomita K. Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15733-8. Epub 2010 Aug 23. PMID:20798060 doi:http://dx.doi.org/10.1073/pnas.1006559107
  2. ↑ Jorgensen R, Merrill AR, Andersen GR. The life and death of translation elongation factor 2. Biochem Soc Trans. 2006 Feb;34(Pt 1):1-6. PMID:16246167 doi:http://dx.doi.org/10.1042/BST20060001
  3. ↑ Kawashima T, Berthet-Colominas C, Wulff M, Cusack S, Leberman R. The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution. Nature. 1996 Feb 8;379(6565):511-8. PMID:8596629 doi:http://dx.doi.org/10.1038/379511a0

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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