1dq4
From Proteopedia
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==A transient unlocked concanavalin A structure with MN2+ bound in the transition metal ion binding site S1 and an empty calcium binding site S2== | ==A transient unlocked concanavalin A structure with MN2+ bound in the transition metal ion binding site S1 and an empty calcium binding site S2== | ||
<StructureSection load='1dq4' size='340' side='right' caption='[[1dq4]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='1dq4' size='340' side='right' caption='[[1dq4]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dq0|1dq0]], [[1dq2|1dq2]], [[1dq1|1dq1]], [[1dq5|1dq5]], [[1dq6|1dq6]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dq0|1dq0]], [[1dq2|1dq2]], [[1dq1|1dq1]], [[1dq5|1dq5]], [[1dq6|1dq6]]</td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq4 OCA], [http://pdbe.org/1dq4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dq4 RCSB], [http://www.ebi.ac.uk/pdbsum/1dq4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq4 OCA], [http://pdbe.org/1dq4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dq4 RCSB], [http://www.ebi.ac.uk/pdbsum/1dq4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dq4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] |
Revision as of 10:35, 3 August 2017
A transient unlocked concanavalin A structure with MN2+ bound in the transition metal ion binding site S1 and an empty calcium binding site S2
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