2x4f
From Proteopedia
(Difference between revisions)
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==The Crystal Structure of the human myosin light chain kinase LOC340156.== | ==The Crystal Structure of the human myosin light chain kinase LOC340156.== | ||
<StructureSection load='2x4f' size='340' side='right' caption='[[2x4f]], [[Resolution|resolution]] 2.67Å' scene=''> | <StructureSection load='2x4f' size='340' side='right' caption='[[2x4f]], [[Resolution|resolution]] 2.67Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16X:4-(2-AMINO-4-METHYL-1,3-THIAZOL-5-YL)-N-(3-DIOXAZIRIDIN-3-YLPHENYL)PYRIMIDIN-2-AMINE'>16X</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16X:4-(2-AMINO-4-METHYL-1,3-THIAZOL-5-YL)-N-(3-DIOXAZIRIDIN-3-YLPHENYL)PYRIMIDIN-2-AMINE'>16X</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x4f OCA], [http://pdbe.org/2x4f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x4f RCSB], [http://www.ebi.ac.uk/pdbsum/2x4f PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x4f OCA], [http://pdbe.org/2x4f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x4f RCSB], [http://www.ebi.ac.uk/pdbsum/2x4f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x4f ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/2x4f_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/2x4f_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2x4f ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2x4f ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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- | ==See Also== | ||
- | *[[Myosin light chain kinase|Myosin light chain kinase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
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[[Category: Cocking, R]] | [[Category: Cocking, R]] | ||
[[Category: Daga, N]] | [[Category: Daga, N]] | ||
- | [[Category: Delft, F | + | [[Category: Delft, F von]] |
[[Category: Edwards, A M]] | [[Category: Edwards, A M]] | ||
[[Category: Elkins, J M]] | [[Category: Elkins, J M]] |
Revision as of 19:07, 24 January 2018
The Crystal Structure of the human myosin light chain kinase LOC340156.
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Categories: Human | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Chaikuad, A | Cocking, R | Daga, N | Delft, F von | Edwards, A M | Elkins, J M | Fedorov, O | Gileadi, O | Knapp, S | Krojer, T | Mahajan, P | Muniz, J R.C | Rellos, P | Shrestha, B | Ugochukwu, E | Wang, J | Weigelt, J | Yue, W | Breast cancer | Kinase | Lung | Myosin | Transferase