1ezj

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[[Image:1ezj.gif|left|200px]]
[[Image:1ezj.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1ezj |SIZE=350|CAPTION= <scene name='initialview01'>1ezj</scene>, resolution 1.90&Aring;
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The line below this paragraph, containing "STRUCTURE_1ezj", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EMC:ETHYL+MERCURY+ION'>EMC</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1ezj| PDB=1ezj | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ezj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ezj OCA], [http://www.ebi.ac.uk/pdbsum/1ezj PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ezj RCSB]</span>
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}}
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'''CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS'''
'''CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS'''
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[[Category: Ruigrok, R W.H.]]
[[Category: Ruigrok, R W.H.]]
[[Category: Tarbouriech, N.]]
[[Category: Tarbouriech, N.]]
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[[Category: four stranded coiled coil]]
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[[Category: Four stranded coiled coil]]
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[[Category: sendai virus]]
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[[Category: Sendai virus]]
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[[Category: tetramer]]
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[[Category: Tetramer]]
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[[Category: viral polymerase]]
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[[Category: Viral polymerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 15:42:23 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:12:45 2008''
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Revision as of 12:42, 2 May 2008

Image:1ezj.gif

Template:STRUCTURE 1ezj

CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS


Overview

The high resolution X-ray structure of the Sendai virus oligomerization domain reveals a homotetrameric coiled coil structure with many details that are different from classic coiled coils with canonical hydrophobic heptad repeats. Alternatives to the classic knobs-into-holes packing lead to differences in supercoil pitch and diameter that allow water molecules inside the core. This open and more hydrophilic structure does not seem to be destabilized by mutations that would be expected to disrupt classic coiled coils.

About this Structure

1EZJ is a Single protein structure of sequence from Sendai virus. Full crystallographic information is available from OCA.

Reference

Tetrameric coiled coil domain of Sendai virus phosphoprotein., Tarbouriech N, Curran J, Ruigrok RW, Burmeister WP, Nat Struct Biol. 2000 Sep;7(9):777-81. PMID:10966649 Page seeded by OCA on Fri May 2 15:42:23 2008

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