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2cg5
From Proteopedia
(Difference between revisions)
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| - | == | + | |
| + | ==Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme A== | ||
<StructureSection load='2cg5' size='340' side='right' caption='[[2cg5]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='2cg5' size='340' side='right' caption='[[2cg5]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2byd|2byd]], [[2c43|2c43]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2byd|2byd]], [[2c43|2c43]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-aminoadipate-semialdehyde_dehydrogenase L-aminoadipate-semialdehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.31 1.2.1.31] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-aminoadipate-semialdehyde_dehydrogenase L-aminoadipate-semialdehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.31 1.2.1.31] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cg5 OCA], [http://pdbe.org/2cg5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cg5 RCSB], [http://www.ebi.ac.uk/pdbsum/2cg5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cg5 OCA], [http://pdbe.org/2cg5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cg5 RCSB], [http://www.ebi.ac.uk/pdbsum/2cg5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cg5 ProSAT]</span></td></tr> |
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/FAS_HUMAN FAS_HUMAN]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cg/2cg5_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cg/2cg5_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2cg5" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2cg5" style="background-color:#fffaf0;"></div> | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Fatty acid synthase|Fatty acid synthase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Arrowsmith, C]] | [[Category: Arrowsmith, C]] | ||
[[Category: Bunkoczi, G]] | [[Category: Bunkoczi, G]] | ||
| - | [[Category: Delft, F | + | [[Category: Delft, F von]] |
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
[[Category: Joshi, A]] | [[Category: Joshi, A]] | ||
Revision as of 18:47, 24 January 2018
Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme A
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Categories: Human | L-aminoadipate-semialdehyde dehydrogenase | Arrowsmith, C | Bunkoczi, G | Delft, F von | Edwards, A | Joshi, A | Oppermann, U | Papagrigoriu, E | Smith, S | Sundstrom, M | Weigelt, J | Acp | Coenzyme some | Complex | Fasn | Fatty acid biosynthesis | Hydrolase | Lipid synthesis | Lyase | Phosphopantetheine transferase | Transferase | Transferase-hydrolase complex
