3a6p
From Proteopedia
(Difference between revisions)
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==Crystal structure of Exportin-5:RanGTP:pre-miRNA complex== | ==Crystal structure of Exportin-5:RanGTP:pre-miRNA complex== | ||
<StructureSection load='3a6p' size='340' side='right' caption='[[3a6p]], [[Resolution|resolution]] 2.92Å' scene=''> | <StructureSection load='3a6p' size='340' side='right' caption='[[3a6p]], [[Resolution|resolution]] 2.92Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3a6p]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3a6p]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Canlf Canlf] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A6P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A6P FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> | ||
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">XPO5, KIAA1291, RANBP21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RAN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">XPO5, KIAA1291, RANBP21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RAN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a6p OCA], [http://pdbe.org/3a6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a6p RCSB], [http://www.ebi.ac.uk/pdbsum/3a6p PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a6p OCA], [http://pdbe.org/3a6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a6p RCSB], [http://www.ebi.ac.uk/pdbsum/3a6p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a6p ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/3a6p_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/3a6p_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Canlf]] |
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Katahira, J]] | [[Category: Katahira, J]] |
Revision as of 08:05, 24 October 2018
Crystal structure of Exportin-5:RanGTP:pre-miRNA complex
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Categories: Canlf | Human | Katahira, J | Lee, S J | Nakagawa, A | Okada, C | Shibata, S | Tsukihara, T | Yamashita, E | Yoneda, Y | Cell cycle | Cell division | Exportin-5 | Gtp-binding | Importin-beta family | Isopeptide bond | Mitosis | Nuclearexport | Nucleotide-binding | Nucleus | Phosphoprotein | Pre-microrna | Protein transport | Protein transport-nuclear protein-rna complex | Rangtp | Rna-binding | Rna-mediated gene silencing | Transport | Trna-binding