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2aob

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==Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain==
==Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain==
<StructureSection load='2aob' size='340' side='right' caption='[[2aob]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2aob' size='340' side='right' caption='[[2aob]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S1S:2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC+ACID'>S1S</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S1S:2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC+ACID'>S1S</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRB2, ASH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRB2, ASH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aob OCA], [http://pdbe.org/2aob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aob RCSB], [http://www.ebi.ac.uk/pdbsum/2aob PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aob OCA], [http://pdbe.org/2aob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aob RCSB], [http://www.ebi.ac.uk/pdbsum/2aob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2aob ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 2aob" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2aob" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Growth factor receptor-bound protein|Growth factor receptor-bound protein]]
 
== References ==
== References ==
<references/>
<references/>

Revision as of 14:28, 12 October 2017

Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain

2aob, resolution 1.80Å

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