4xui
From Proteopedia
(Difference between revisions)
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==Crystal structure analysis of cruzain bound to the no-covalent analog of WRR-483 (WRR-669)== | ==Crystal structure analysis of cruzain bound to the no-covalent analog of WRR-483 (WRR-669)== | ||
| - | <StructureSection load='4xui' size='340' side='right' caption='[[4xui]], [[Resolution|resolution]] 2.51Å' scene=''> | + | <StructureSection load='4xui' size='340' side='right'caption='[[4xui]], [[Resolution|resolution]] 2.51Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4xui]] is a 3 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4pi4 4pi4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XUI FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4xui]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4pi4 4pi4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XUI FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2VC:N-[(2S)-5-(CARBAMIMIDAMIDOOXY)-1-OXO-1-{[(1E,3S)-5-PHENYL-1-(PYRIMIDIN-2-YLSULFONYL)PENT-1-EN-3-YL]AMINO}PENTAN-2-YL]-4-METHYLPIPERAZINE-1-CARBOXAMIDE'>2VC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2VC:N-[(2S)-5-(CARBAMIMIDAMIDOOXY)-1-OXO-1-{[(1E,3S)-5-PHENYL-1-(PYRIMIDIN-2-YLSULFONYL)PENT-1-EN-3-YL]AMINO}PENTAN-2-YL]-4-METHYLPIPERAZINE-1-CARBOXAMIDE'>2VC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pi3|4pi3]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pi3|4pi3]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cruzipain Cruzipain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.51 3.4.22.51] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cruzipain Cruzipain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.51 3.4.22.51] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xui OCA], [http://pdbe.org/4xui PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xui RCSB], [http://www.ebi.ac.uk/pdbsum/4xui PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xui OCA], [http://pdbe.org/4xui PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xui RCSB], [http://www.ebi.ac.uk/pdbsum/4xui PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xui ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4xui" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4xui" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Cruzain|Cruzain]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Cruzipain]] | [[Category: Cruzipain]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Trycr]] | ||
[[Category: McKerrow, J H]] | [[Category: McKerrow, J H]] | ||
[[Category: Tochowicz, A]] | [[Category: Tochowicz, A]] | ||
Revision as of 23:45, 5 June 2019
Crystal structure analysis of cruzain bound to the no-covalent analog of WRR-483 (WRR-669)
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