M2 protein

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{{STRUCTURE_3c9j| PDB=3c9j | SIZE=350| SCENE= |right| CAPTION=Transmembrane domain of M2 protein from influenza A virus complex with amantadine, [[3c9j]] }}
 
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The '''M2 protein''' (M2) is a proton selective ion channelof the infl;uenza virus. It is activated by low pH. M2 has 3 domains: an ectodomain, transmembrane domain (TM) and a C terminal cytoplasmic domain. See more in:<br />
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<StructureSection load='4c3e' size='350' side='right' caption='Human α-defensin 1 (PDB entry [[2pm4]])' scene=''>
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__TOC__
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== Function ==
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The '''M2 protein''' (M2) is a proton selective ion channel of the influenza virus<ref>PMID:18045172</ref>. It is activated by low pH. M2 has 3 domains: an ectodomain, transmembrane domain (TM) and a C terminal cytoplasmic domain. See more in:<br />
[[M2 Proton Channel]]<br />
[[M2 Proton Channel]]<br />
[[Molecular Playground/Influenza A M2 transmembrane domain]]<br />
[[Molecular Playground/Influenza A M2 transmembrane domain]]<br />
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[[4c3e]] – hrsvM2 (mutant)<br />
[[4c3e]] – hrsvM2 (mutant)<br />
[[2l9j]] – hrsvM2 core domain (mutant) - NMR<br />
[[2l9j]] – hrsvM2 core domain (mutant) - NMR<br />
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 06:59, 14 April 2016

Human α-defensin 1 (PDB entry 2pm4)

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Michal Harel, Alexander Berchansky

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