Nuclear transcription factor Y
From Proteopedia
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'''Nuclear transcription factor Y''' (NFY) binds to a CCAAT sequence of gene promoters. NFY contains 3 subunits while subunit α binds the promoter box sequence<ref>PMID:9612081</ref>. See details in [[NF-Y Transcription Factor]]. | '''Nuclear transcription factor Y''' (NFY) binds to a CCAAT sequence of gene promoters. NFY contains 3 subunits while subunit α binds the promoter box sequence<ref>PMID:9612081</ref>. See details in [[NF-Y Transcription Factor]]. | ||
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| - | == Disease == | ||
== Relevance == | == Relevance == | ||
NFY is a regulatory factor for many genes which are overexpressed in many kinds of cancer. | NFY is a regulatory factor for many genes which are overexpressed in many kinds of cancer. | ||
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| - | == Structural highlights == | ||
</StructureSection> | </StructureSection> | ||
Revision as of 10:57, 16 February 2016
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3D Structures of nuclear transcription factor Y
Updated on 16-February-2016
1n1j, 4csr – hNFY β+γ subunits - human
4awl – hNFY α+β+γ subunits + promoter DNA
References
- ↑ Maity SN, de Crombrugghe B. Role of the CCAAT-binding protein CBF/NF-Y in transcription. Trends Biochem Sci. 1998 May;23(5):174-8. PMID:9612081
