Neuroligin
From Proteopedia
(Difference between revisions)
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| - | [[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic [[Neurexin]] (NRXN) to form a complex which attaches neurons. In humans the NLGN family contains 4 to 5 members that are numbered 1, 2, 3, 4X and 5 or 4Y | + | [[Neuroligin|Neuroligins]] (NLGN) are a family of postsynaptic proteins which bind to the presynaptic [[Neurexin]] (NRXN) to form a complex which attaches neurons. In humans the NLGN family contains 4 to 5 members that are numbered 1, 2, 3, 4X and 5 or 4Y<ref>PMID:18093521</ref>. |
| - | + | See [[Neurodevelopmental Disorders]]<br /> | |
| + | |||
| + | [[Neuroligin-Neurexin Interaction]] | ||
== 3D Structures of Neuroligin == | == 3D Structures of Neuroligin == | ||
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**[[3vkf]] - rNLGN-1 cholinesterase domain + bNRXN-1β LNS domain | **[[3vkf]] - rNLGN-1 cholinesterase domain + bNRXN-1β LNS domain | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:49, 9 May 2016
Image:3be8a.png
Crystal Structure of human Neuroligin 3be8
Neuroligins (NLGN) are a family of postsynaptic proteins which bind to the presynaptic Neurexin (NRXN) to form a complex which attaches neurons. In humans the NLGN family contains 4 to 5 members that are numbered 1, 2, 3, 4X and 5 or 4Y[1].
See Neurodevelopmental Disorders
Neuroligin-Neurexin Interaction
3D Structures of Neuroligin
09-May-2016
References
- ↑ Fabrichny IP, Leone P, Sulzenbacher G, Comoletti D, Miller MT, Taylor P, Bourne Y, Marchot P. Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion. Neuron. 2007 Dec 20;56(6):979-91. PMID:18093521 doi:10.1016/j.neuron.2007.11.013
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Joel L. Sussman, Pascale Marchot, Jaime Prilusky, David Canner
