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Ribonucleotide reductase
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For details on human RNR2 see [[P53R2]].<br /> | For details on human RNR2 see [[P53R2]].<br /> | ||
For mouse RNR see [[Mouse Ribonucleotide Reductase R2]].<br /> | For mouse RNR see [[Mouse Ribonucleotide Reductase R2]].<br /> | ||
| - | For RNR small subunit with | + | For RNR small subunit with nitrotyrosine modification see [[Nitroltyrosine]]. |
== 3D Structures of Ribonucleotide reductase == | == 3D Structures of Ribonucleotide reductase == | ||
Revision as of 11:28, 16 February 2016
Ribonucleotide reductase (RNR) catalyzes the formation of deoxyribonucleotides from ribonucleotides. There are 3 classes of RNR.
- Class I RNR is a tetramer composed from large (RNR1) and small (RNR2) subunits. Class I RNR is iron-dependent and produces tyrosyl radical. Thimidine triphosphate (TTP) is an effector in the reaction.
- Class II RNR reduces ribonucleotide triphosphates using coenzyme B12.
- Class III RNR generate glycine radical using S-adenosyl methionine and Fe-S center.
For details on human RNR2 see P53R2.
For mouse RNR see Mouse Ribonucleotide Reductase R2.
For RNR small subunit with nitrotyrosine modification see Nitroltyrosine.
3D Structures of Ribonucleotide reductase
Updated on 16-February-2016
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