Phosphoinositide phosphatase
From Proteopedia
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| - | <StructureSection load='3mtc' size=' | + | <StructureSection load='3mtc' size='350' side='right' caption='Human 5PTase complex with phosphoinositol 4-phospate, glycerol, sulfate, Cl- (green) and Mg+2 (light green) ions (PDB code [[3mtc]])' scene='72/725405/Cv/1'> |
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
| - | The substrate binds to one terminus of the β sandwich<ref>PMID:24704254</ref>. | + | The <scene name='72/725405/Cv/2'>substrate binds to one terminus of the β sandwich</scene><ref>PMID:24704254</ref>. |
</StructureSection> | </StructureSection> | ||
Revision as of 12:18, 17 February 2016
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3D Structures of phosphoinositide phosphatase
Updated on 17-February-2016
References
- ↑ Dyson JM, Fedele CG, Davies EM, Becanovic J, Mitchell CA. Phosphoinositide phosphatases: just as important as the kinases. Subcell Biochem. 2012;58:215-79. doi: 10.1007/978-94-007-3012-0_7. PMID:22403078 doi:http://dx.doi.org/10.1007/978-94-007-3012-0_7
- ↑ Tresaugues L, Silvander C, Flodin S, Welin M, Nyman T, Graslund S, Hammarstrom M, Berglund H, Nordlund P. Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases. Structure. 2014 Apr 2. pii: S0969-2126(14)00073-2. doi:, 10.1016/j.str.2014.01.013. PMID:24704254 doi:http://dx.doi.org/10.1016/j.str.2014.01.013
