This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5ctu
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment== | ==Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment== | ||
| - | <StructureSection load='5ctu' size='340' side='right' caption='[[5ctu]], [[Resolution|resolution]] 1.45Å' scene=''> | + | <StructureSection load='5ctu' size='340' side='right'caption='[[5ctu]], [[Resolution|resolution]] 1.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ctu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CTU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CTU FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5ctu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CTU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CTU FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=54X:5-(THIOPHEN-2-YL)THIENO[2,3-D]PYRIMIDIN-4(1H)-ONE'>54X</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=54X:5-(THIOPHEN-2-YL)THIENO[2,3-D]PYRIMIDIN-4(1H)-ONE'>54X</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cph|5cph]], [[5ctw|5ctw]], [[5ctx|5ctx]], [[5cty|5cty]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cph|5cph]], [[5ctw|5ctw]], [[5ctx|5ctx]], [[5cty|5cty]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ctu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ctu OCA], [http://pdbe.org/5ctu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ctu RCSB], [http://www.ebi.ac.uk/pdbsum/5ctu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ctu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ctu OCA], [http://pdbe.org/5ctu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ctu RCSB], [http://www.ebi.ac.uk/pdbsum/5ctu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ctu ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 20: | Line 21: | ||
</div> | </div> | ||
<div class="pdbe-citations 5ctu" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5ctu" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Gyrase 3D Structures|Gyrase 3D Structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Andersen, O A]] | [[Category: Andersen, O A]] | ||
[[Category: Barker, J]] | [[Category: Barker, J]] | ||
Revision as of 10:23, 1 April 2020
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
| |||||||||||
Categories: Large Structures | Andersen, O A | Barker, J | Cheng, R K | Cross, J B | Felicetti, B | Kahmann, J | Lippa, B | Mesleh, M | Ryan, M D | Scheich, C | Wood, M | Yang, Q | Zhang, J | Dna gyrase | Fragment-based screening | Gyrb | Isomerase | Structure-based design
