5fu8

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'''Unreleased structure'''
 
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The entry 5fu8 is ON HOLD until Paper Publication
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==Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor==
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<StructureSection load='5fu8' size='340' side='right' caption='[[5fu8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Alphey, M.S., Tran, F., Westwood, N.J., Naismith, J.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5fu8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FU8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FU8 FirstGlance]. <br>
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Description: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DH5:N-(6-AMINO-1-(4-BROMO-3-METHYLBENZYL)-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)-N-METHYLBENZENESULFONAMIDE'>DH5</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_thymidylyltransferase Glucose-1-phosphate thymidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.24 2.7.7.24] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fu8 OCA], [http://pdbe.org/5fu8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fu8 RCSB], [http://www.ebi.ac.uk/pdbsum/5fu8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fu8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q9HU22_PSEAE Q9HU22_PSEAE]] Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity).[RuleBase:RU003706]
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__TOC__
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</StructureSection>
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[[Category: Glucose-1-phosphate thymidylyltransferase]]
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[[Category: Alphey, M S]]
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[[Category: Naismith, J H]]
[[Category: Tran, F]]
[[Category: Tran, F]]
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[[Category: Naismith, J.H]]
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[[Category: Westwood, N J]]
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[[Category: Westwood, N.J]]
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[[Category: Allosteric]]
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[[Category: Alphey, M.S]]
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[[Category: Inhibitor]]
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[[Category: Pseudomona]]
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[[Category: Thymidylyl]]
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[[Category: Transferase]]

Revision as of 01:30, 11 March 2017

Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor

5fu8, resolution 2.20Å

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