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B-DNA tour
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<UL> | <UL> | ||
| - | <LI> Most common DNA conformation in vivo | + | <LI> Most common DNA conformation ''in vivo'' |
| - | <LI> Narrower, more elongated helix than A | + | <LI> Narrower, more elongated helix than A-form |
<LI> Wide major groove easily accessible to proteins | <LI> Wide major groove easily accessible to proteins | ||
<LI> Narrow minor groove | <LI> Narrow minor groove | ||
<LI> Favored conformation at high water concentrations (hydration of minor groove seems to favor B-form) | <LI> Favored conformation at high water concentrations (hydration of minor groove seems to favor B-form) | ||
<LI> Base pairs nearly perpendicular to helix axis | <LI> Base pairs nearly perpendicular to helix axis | ||
| - | <LI> Sugar pucker C2'-endo | + | <LI> Sugar pucker C2'-''endo'' |
</UL> | </UL> | ||
Revision as of 14:01, 21 February 2016
B-form DNA
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References
R. E. Dickerson, H. R. Drew, B. N. Conner, R. M. Wing, A. V. Fratini & M. L. Kopka (1982) The anatomy of A-, B-, and Z-DNA. Science 216: 475-485 [1] JSmol in Proteopedia [2] or to the article describing Jmol [3] to the rescue.
