Sandbox Reserved 430
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==Binding Interactions== | ==Binding Interactions== | ||
<Structure load='4ntj' size='300' frame='true' align='right' caption='pdbcode, Insert caption here' scene='Insert optional scene name here' /> | <Structure load='4ntj' size='300' frame='true' align='right' caption='pdbcode, Insert caption here' scene='Insert optional scene name here' /> | ||
- | <scene name='48/ | + | The <scene name='48/483887/Binding_site/4'>Binding Site</scene> of P2Y12 is colored in purple, which is the burried site, along with the ligands, which is colored in yellow. |
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Revision as of 05:02, 27 February 2016
This Sandbox is Reserved from January 19, 2016, through August 31, 2016 for use for Proteopedia Team Projects by the class Chemistry 423 Biochemistry for Chemists taught by Lynmarie K Thompson at University of Massachusetts Amherst, USA. This reservation includes Sandbox Reserved 425 through Sandbox Reserved 439. |
Contents |
P2Y12 Receptor in Complex with Clopidogrel (4ntj)[1]
by [Cora Ricker, Lauren Timmins, Aidan Finnerty, Adam Murphy, Duy Nguyen]
Student Projects for UMass Chemistry 423 Spring 2016
Introduction
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.
Overall Structure
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The is mostly made up of alpha helices, shown in pink. The beta strands are shown in yellow. Polar vs nonpolar:Polar regions are pink. Nonpolar, or hyrophobic, regions are grey.
Binding Interactions
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The of P2Y12 is colored in purple, which is the burried site, along with the ligands, which is colored in yellow.
Additional Features
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Quiz Question 1
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See Also
Credits
Introduction - Adam Murphy
Overall Structure - Cora Ricker
Drug Binding Site - name of team member
Additional Features - name of team member
Quiz Question 1 - name of team member
References
- ↑ Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Muller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, Stevens RC, Wu B, Zhao Q. Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature. 2014 May 1;509(7498):115-8. doi: 10.1038/nature13083. Epub 2014 Mar 23. PMID:24670650 doi:http://dx.doi.org/10.1038/nature13083