4ql1
From Proteopedia
(Difference between revisions)
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==Crystal structure of human WDR5 in complex with compound OICR-9429== | ==Crystal structure of human WDR5 in complex with compound OICR-9429== | ||
- | <StructureSection load='4ql1' size='340' side='right' caption='[[4ql1]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='4ql1' size='340' side='right'caption='[[4ql1]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4ql1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QL1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QL1 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4ql1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QL1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QL1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35Q:N-(4-(4-METHYLPIPERAZIN-1-YL)-3-(MORPHOLINOMETHYL)-[1,1-BIPHENYL]-3-YL)-6-OXO-4-(TRIFLUOROMETHYL)-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>35Q</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35Q:N-(4-(4-METHYLPIPERAZIN-1-YL)-3-(MORPHOLINOMETHYL)-[1,1-BIPHENYL]-3-YL)-6-OXO-4-(TRIFLUOROMETHYL)-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>35Q</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ql1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ql1 OCA], [http://pdbe.org/4ql1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ql1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ql1 PDBsum]</span></td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">WDR5, BIG3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ql1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ql1 OCA], [http://pdbe.org/4ql1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ql1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ql1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ql1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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==See Also== | ==See Also== | ||
- | *[[WD | + | *[[WD repeat-containing protein|WD repeat-containing protein]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Human]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Al-Awar, R]] | [[Category: Al-Awar, R]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] |
Revision as of 09:22, 24 April 2019
Crystal structure of human WDR5 in complex with compound OICR-9429
|
Categories: Human | Large Structures | Al-Awar, R | Arrowsmith, C H | Barsyte, D | Bountra, C | Brown, P J | Dombrovski, L | Dong, A | Edwards, A M | Getlik, M | Kuznetsova, E | Li, F | Marcellus, R | Poda, G | Structural genomic | Schapira, M | Senisterra, G | Smil, D | Vedadi, M | Walker, J R | Wu, H | Oicr-9429 inhibitor | Sgc | Transcription-inhibitor complex | Wd repeat domain 5 | Wdr5