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Sandbox Wabash 27 Fumarase

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== Relevance ==
== Relevance ==
 +
In order to determine the true catalytic site the two histindines at site A and B were mutated. This was determined to be the appropriate approach by anaylsis of biochemical data which suggested that a histidine residue was participating in the catalytic process.
== Structural highlights ==
== Structural highlights ==

Revision as of 00:36, 28 February 2016

Fumarase: Active site and intermediates

Fumarase

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References

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
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