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Sandbox Wabash 13
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==Distinguishing between the active site and a nearby dicarboxylic acid binding site in Fumarase== | ==Distinguishing between the active site and a nearby dicarboxylic acid binding site in Fumarase== | ||
In early studies, two carboxylic acid binding sites, subsequently named A- and B-, were observed in the wild type crystal structure of fumarase C in ''E. Coli.'' The structures of these two sites was considerably different as site A contained atom of three of the four subunits of fumarase C whereas site B contained only atoms from a single subunit of the tetramer. | In early studies, two carboxylic acid binding sites, subsequently named A- and B-, were observed in the wild type crystal structure of fumarase C in ''E. Coli.'' The structures of these two sites was considerably different as site A contained atom of three of the four subunits of fumarase C whereas site B contained only atoms from a single subunit of the tetramer. | ||
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== References == | == References == | ||
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<ref group="xtra">PMID:9098893</ref><references group="xtra"/> | <ref group="xtra">PMID:9098893</ref><references group="xtra"/> | ||
Revision as of 03:50, 28 February 2016
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