Sandbox Wabash07
From Proteopedia
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==Fumarase Active Site== | ==Fumarase Active Site== | ||
| - | <StructureSection load='1yfe' size='340' side='right' caption=' | + | <StructureSection load='1yfe' size='340' side='right' caption='Fumarase' scene=''> |
Trypsin is a Serine protease. It catalyzes peptide bond hydrolysis in two sequential steps. In the first (acylation) reaction, the nucleophilic serine attacks the substrate scissile bond, forming first a tetrahedral intermediate and then a covalent acyl-enzyme with release of the C-terminal fragment. In the second (deacylation) reaction, a water molecule attacks the acyl-enzyme, leading to a second tetrahedral intermediate followed by release of the N-terminal fragment. '''Sandbox Wabash07'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | Trypsin is a Serine protease. It catalyzes peptide bond hydrolysis in two sequential steps. In the first (acylation) reaction, the nucleophilic serine attacks the substrate scissile bond, forming first a tetrahedral intermediate and then a covalent acyl-enzyme with release of the C-terminal fragment. In the second (deacylation) reaction, a water molecule attacks the acyl-enzyme, leading to a second tetrahedral intermediate followed by release of the N-terminal fragment. '''Sandbox Wabash07'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
Revision as of 18:34, 28 February 2016
Fumarase Active Site
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
