User:Christopher Berndsen/Labinfo
From Proteopedia
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==The Berndsen Laboratory at James Madison University== | ==The Berndsen Laboratory at James Madison University== | ||
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | The Berndsen Lab is located in the [http://www.jmu.edu/chemistry/ Department of Chemistry and Biochemistry] at [http://www.jmu.edu James Madison University] in Harrisonburg, VA. The primary research focus is the mechanism enzymes involved in the conjugation and processing of ubiquitin and ubiquitin-like proteins. | + | The Berndsen Lab is located in the [http://www.jmu.edu/chemistry/ Department of Chemistry and Biochemistry] at [http://www.jmu.edu James Madison University] in Harrisonburg, VA. The primary research focus is the mechanism enzymes involved in the conjugation and processing of ubiquitin and ubiquitin-like proteins. Additionally, the lab is interested in integrating protein structure research and molecular basis for disease into the biochemistry classroom. |
| - | == | + | == Research Highlights == |
| + | Ubiquitin and Ubiquitin-like proteins are linked to many cellular functions included protein degradation and DNA damage repair <ref>PMID:15571809<ref><ref>PMID:24699078<ref>. The Berndsen Lab is interested in the catalytic mechanisms the conjugating enzymes E1, E2, and E3 use to attach ubiquitin/ubiquitin-like proteins to the substrate lysine. We are also interested in the proteases that remove these modifications and the chemical mechanism(s) of catalysis. We are currently focusing on UFM1<Structure load='1WXS' size='350' frame='true' align='right' caption='NMR Structure of UFM1 from <ref>PMID:16527251<ref>' scene='UFM1' /> | ||
== Disease == | == Disease == | ||
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== Structural highlights == | == Structural highlights == | ||
| - | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 19:39, 1 March 2016
The Berndsen Laboratory at James Madison University
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References
- ↑ PMID:15571809<ref><ref>PMID:24699078<ref>. The Berndsen Lab is interested in the catalytic mechanisms the conjugating enzymes E1, E2, and E3 use to attach ubiquitin/ubiquitin-like proteins to the substrate lysine. We are also interested in the proteases that remove these modifications and the chemical mechanism(s) of catalysis. We are currently focusing on UFM1<Structure load='1WXS' size='350' frame='true' align='right' caption='NMR Structure of UFM1 from <ref>PMID:16527251<ref>' scene='UFM1' /> == Disease == == Relevance == == Structural highlights == </li></ol></ref>
