5ant
From Proteopedia
(Difference between revisions)
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==Potent and selective inhibitors of MTH1 probe its role in cancer cell survival== | ==Potent and selective inhibitors of MTH1 probe its role in cancer cell survival== | ||
| - | <StructureSection load='5ant' size='340' side='right' caption='[[5ant]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='5ant' size='340' side='right'caption='[[5ant]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ant]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ANT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ANT FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5ant]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ANT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ANT FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RJE:2-(2-METHOXYETHOXY)-6-(METHYLAMINO)-9-(PHENYLMETHYL)-7H-PURIN-8-ONE'>RJE</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RJE:2-(2-METHOXYETHOXY)-6-(METHYLAMINO)-9-(PHENYLMETHYL)-7H-PURIN-8-ONE'>RJE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5anm|5anm]], [[5ans|5ans]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5anm|5anm]], [[5ans|5ans]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ant FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ant OCA], [http://pdbe.org/5ant PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ant RCSB], [http://www.ebi.ac.uk/pdbsum/5ant PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ant FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ant OCA], [http://pdbe.org/5ant PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ant RCSB], [http://www.ebi.ac.uk/pdbsum/5ant PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ant ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5ant" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5ant" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[7%2C8-dihydro-8-oxoguanine triphosphatase 3D structures|7%2C8-dihydro-8-oxoguanine triphosphatase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Alwan, H]] | [[Category: Alwan, H]] | ||
[[Category: Bista, M]] | [[Category: Bista, M]] | ||
Revision as of 07:18, 3 July 2019
Potent and selective inhibitors of MTH1 probe its role in cancer cell survival
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Categories: Human | Large Structures | Alwan, H | Bista, M | Breed, J | Eckersley, K | Fillery, S | Foote, K M | Goodwin, L | Jones, D | Kack, H | Kettle, J G | Lau, A | Nissink, J W.M | Read, J | Scott, J | Taylor, B | Walker, G | Wissler, L | Hydrolase | Inhibition | Mth1 | Nucleotide hydrolysis | Oncology
