5fwc

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'''Unreleased structure'''
 
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The entry 5fwc is ON HOLD until Paper Publication
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==Human Spectrin SH3 domain D48G, E7A, K60A==
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<StructureSection load='5fwc' size='340' side='right' caption='[[5fwc]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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Authors: Gallego, P., Navarro, S., Ventura, S., Reverter, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5fwc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FWC FirstGlance]. <br>
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Description: Human Spectrin SH3 domain D48G, E7A, K60A
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fw6|5fw6]], [[5fw7|5fw7]], [[5fw8|5fw8]], [[5fw9|5fw9]], [[5fwb|5fwb]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwc OCA], [http://pdbe.org/5fwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fwc RCSB], [http://www.ebi.ac.uk/pdbsum/5fwc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwc ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN]] West syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN]] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
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__TOC__
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</StructureSection>
[[Category: Gallego, P]]
[[Category: Gallego, P]]
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[[Category: Navarro, S]]
[[Category: Reverter, D]]
[[Category: Reverter, D]]
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[[Category: Navarro, S]]
 
[[Category: Ventura, S]]
[[Category: Ventura, S]]
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[[Category: Spectrin sh3]]
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[[Category: Structural protein]]

Revision as of 16:22, 2 January 2017

Human Spectrin SH3 domain D48G, E7A, K60A

5fwc, resolution 1.40Å

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