Glucose-fructose oxidoreductase
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='1h6b' size=' | + | <StructureSection load='1h6b' size='450' side='right' caption='Glucose-fructose oxidoreductase complex with NADPH and glycerol (PDB entry [[1evj]])' scene='49/490077/Cv/1'> |
== Function == | == Function == | ||
'''Glucose-fructose oxidoreductase''' (GFOR) from the bacteria ''Zymomonas mobilis'' catalyzes the conversion of D-glucose and D-fructose to D-gluconolactone and D-glucitol (sorbitol)<ref>PMID:3356190</ref>. GFOR contains a tightly bound cofactor NADP+. | '''Glucose-fructose oxidoreductase''' (GFOR) from the bacteria ''Zymomonas mobilis'' catalyzes the conversion of D-glucose and D-fructose to D-gluconolactone and D-glucitol (sorbitol)<ref>PMID:3356190</ref>. GFOR contains a tightly bound cofactor NADP+. | ||
== Structural highlights == | == Structural highlights == | ||
| - | The biological assembly of GFOR from ''Zymomonas mobilis'' is <scene name='49/490077/Cv/2'>homotetramer</scene>. GFOR active site contains the cofactor | + | The biological assembly of GFOR from ''Zymomonas mobilis'' is <scene name='49/490077/Cv/2'>homotetramer</scene>. <scene name='49/490077/Cv/7'>GFOR active site contains the cofactor NADPH</scene> and in this 3D structure the <scene name='49/490077/Cv/7'>glycerol molecule seen in the active site occupies the position of the glucose ligand</scene><ref>PMID:11705375</ref>. |
==3D structures of glucose-fructose oxidoreductase== | ==3D structures of glucose-fructose oxidoreductase== | ||
Revision as of 09:05, 13 March 2016
| |||||||||||
