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Sandbox Reserved 1165

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==Introduction==
==Introduction==
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<scene name='72/721536/Class_b_receptor/1'>Human glucagon class B G protein-coupled receptors (GPCRs)</scene>, also known as secretin-like receptors, are a subfamily of the more well known class A ([https://en.wikipedia.org/wiki/Rhodopsin-like_receptors rhodopsin-like]) glucagon receptor family. Located in the liver, class B glucagon receptors (GCGRs) are activated by the binding of the hormonal peptide ([https://en.wikipedia.org/wiki/Glucagon glucagon]) which leads to the release of glucose into the bloodstream and plays an essential role in [https://en.wikipedia.org/wiki/Glucose glucose] homeostasis. Class B GCGRs are composed of a seven transmembrane domain (7TM) and extracellular domain (EC) that are of vital importance in glucagon binding. In comparison, class A vs. class B glucagon receptors share less than fifteen percent sequence homology, but both share this 7TM which is a primary area of comparison between the two.
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<scene name='72/721536/Class_b_receptor/1'>Human glucagon class B G protein-coupled receptors (GPCRs)</scene>, also known as secretin-like receptors, are a subfamily of the more well known class A ([https://en.wikipedia.org/wiki/Rhodopsin-like_receptors rhodopsin-like]) glucagon receptor family. Located in the liver, class B glucagon receptors (GCGRs) are activated by the binding of the hormonal peptide [https://en.wikipedia.org/wiki/Glucagon glucagon] which leads to the release of glucose into the bloodstream and plays an essential role in [https://en.wikipedia.org/wiki/Glucose glucose] homeostasis. Class B GCGRs are composed of a seven transmembrane domain (7TM) and extracellular domain (EC) that are of vital importance in glucagon binding. In comparison, class A vs. class B glucagon receptors share less than fifteen percent sequence homology, but both share this 7TM which is a primary area of comparison between the two.
== Function ==
== Function ==

Revision as of 13:17, 15 March 2016

[[Image:]]

This Sandbox is Reserved from Jan 11 through August 12, 2016 for use in the course CH462 Central Metabolism taught by R. Jeremy Johnson at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1160 through Sandbox Reserved 1184.
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Human Glucagon Class B G Protein-Coupled Receptors (GPCRs)

Class B 7TM

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References

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