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Gramicidin

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<StructureSection load='2xdc' size='350' side='right' caption='Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine (PDB entry [[2xds]])' scene=''>
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<StructureSection load='2xds' size='350' side='right' caption='Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine (PDB entry [[2xds]])' scene=''>
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== Function ==
== Function ==
[[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It is produced by the bacteria ''Bacillus brevis''<ref>PMID:5288776</ref>.<br />
[[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It is produced by the bacteria ''Bacillus brevis''<ref>PMID:5288776</ref>.<br />

Revision as of 08:56, 16 March 2016

Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with PEG 1500 and ethanolamine (PDB entry 2xds)

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3D Structures of Gramicidin

Updated on 16-March-2016

References

  1. Urry DW, Goodall MC, Glickson JD, Mayers DF. The gramicidin A transmembrane channel: characteristics of head-to-head dimerized (L,D) helices. Proc Natl Acad Sci U S A. 1971 Aug;68(8):1907-11. PMID:5288776
  2. Kondejewski LH, Farmer SW, Wishart DS, Hancock RE, Hodges RS. Gramicidin S is active against both gram-positive and gram-negative bacteria. Int J Pept Protein Res. 1996 Jun;47(6):460-6. PMID:8836773

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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