Sandbox Reserved 1170
From Proteopedia
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== Function == | == Function == | ||
| + | Human GPR40 is a G-protein couple receptor that binds free fatty acids to enhance glucose dependent insulin signaling.<ref name="Srivastava">PMID:25043059</ref> | ||
== Structure == | == Structure == | ||
<scene name='72/721541/Stabilizing_mutations/3'>Stabilizing Mutations</scene> | <scene name='72/721541/Stabilizing_mutations/3'>Stabilizing Mutations</scene> | ||
Revision as of 13:32, 22 March 2016
Human GPR40
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Srivastava A, Yano J, Hirozane Y, Kefala G, Gruswitz F, Snell G, Lane W, Ivetac A, Aertgeerts K, Nguyen J, Jennings A, Okada K. High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875. Nature. 2014 Jul 20. doi: 10.1038/nature13494. PMID:25043059 doi:http://dx.doi.org/10.1038/nature13494
