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1h1l

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[[Image:1h1l.jpg|left|200px]]
[[Image:1h1l.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1h1l |SIZE=350|CAPTION= <scene name='initialview01'>1h1l</scene>, resolution 1.90&Aring;
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The line below this paragraph, containing "STRUCTURE_1h1l", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=CT1:Clf+Binding+Site+For+Chain+D'>CT1</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CFM:FE-MO-S+CLUSTER'>CFM</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CLF:FE(8)-S(7)+CLUSTER'>CLF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrogenase Nitrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.6.1 1.18.6.1] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1h1l| PDB=1h1l | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h1l OCA], [http://www.ebi.ac.uk/pdbsum/1h1l PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1h1l RCSB]</span>
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}}
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'''NITROGENASE MO-FE PROTEIN FROM KLEBSIELLA PNEUMONIAE, NIFV MUTANT'''
'''NITROGENASE MO-FE PROTEIN FROM KLEBSIELLA PNEUMONIAE, NIFV MUTANT'''
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[[Category: Mayer, S M.]]
[[Category: Mayer, S M.]]
[[Category: Smith, B E.]]
[[Category: Smith, B E.]]
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[[Category: biological nitrogen fixation]]
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[[Category: Biological nitrogen fixation]]
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[[Category: electron transfer]]
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[[Category: Electron transfer]]
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[[Category: molybdoenzyme]]
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[[Category: Molybdoenzyme]]
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[[Category: nitrogen metabolism]]
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[[Category: Nitrogen metabolism]]
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[[Category: oxidoreductase]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:18:07 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:55:49 2008''
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Revision as of 15:18, 2 May 2008

Image:1h1l.jpg

Template:STRUCTURE 1h1l

NITROGENASE MO-FE PROTEIN FROM KLEBSIELLA PNEUMONIAE, NIFV MUTANT


Overview

The x-ray crystal structure of NifV(-) Klebsiella pneumoniae nitrogenase MoFe protein (NifV(-) Kp1) has been determined and refined to a resolution of 1.9 A. This is the first structure for a nitrogenase MoFe protein with an altered cofactor. Moreover, it is the first direct evidence that the organic acid citrate is not just present, but replaces homocitrate as a ligand to the molybdenum atom of the iron molybdenum cofactor (FeMoco). Subsequent refinement of the structure revealed that the citrate was present at reduced occupancy.

About this Structure

1H1L is a Protein complex structure of sequences from Klebsiella pneumoniae. Full crystallographic information is available from OCA.

Reference

Crystallographic analysis of the MoFe protein of nitrogenase from a nifV mutant of Klebsiella pneumoniae identifies citrate as a ligand to the molybdenum of iron molybdenum cofactor (FeMoco)., Mayer SM, Gormal CA, Smith BE, Lawson DM, J Biol Chem. 2002 Sep 20;277(38):35263-6. Epub 2002 Jul 19. PMID:12133839 Page seeded by OCA on Fri May 2 18:18:07 2008

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