1h21

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1h21.jpg|left|200px]]
[[Image:1h21.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1h21 |SIZE=350|CAPTION= <scene name='initialview01'>1h21</scene>, resolution 2.50&Aring;
+
The line below this paragraph, containing "STRUCTURE_1h21", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=AC1:Hec+Binding+Site+For+Chain+D'>AC1</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=HEC:HEME+C'>HEC</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1h21| PDB=1h21 | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h21 OCA], [http://www.ebi.ac.uk/pdbsum/1h21 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1h21 RCSB]</span>
+
-
}}
+
'''A NOVEL IRON CENTRE IN THE SPLIT-SORET CYTOCHROME C FROM DESULFOVIBRIO DESULFURICANS ATCC 27774'''
'''A NOVEL IRON CENTRE IN THE SPLIT-SORET CYTOCHROME C FROM DESULFOVIBRIO DESULFURICANS ATCC 27774'''
Line 19: Line 16:
==About this Structure==
==About this Structure==
-
1H21 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans]. This structure supersedes the now removed PDB entry 1DDC. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H21 OCA].
+
1H21 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ddc 1ddc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H21 OCA].
==Reference==
==Reference==
Line 35: Line 32:
[[Category: Teixeira, M.]]
[[Category: Teixeira, M.]]
[[Category: Xavier, A V.]]
[[Category: Xavier, A V.]]
-
[[Category: dimeric di-heme cytochrome]]
+
[[Category: Dimeric di-heme cytochrome]]
-
[[Category: electron transport]]
+
[[Category: Electron transport]]
-
[[Category: novel fold]]
+
[[Category: Novel fold]]
-
[[Category: novel iron-sulfur centre]]
+
[[Category: Novel iron-sulfur centre]]
-
[[Category: stacked heme arrangement]]
+
[[Category: Stacked heme arrangement]]
-
[[Category: sulfate respiration]]
+
[[Category: Sulfate respiration]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:19:14 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:56:03 2008''
+

Revision as of 15:19, 2 May 2008

Image:1h21.jpg

Template:STRUCTURE 1h21

A NOVEL IRON CENTRE IN THE SPLIT-SORET CYTOCHROME C FROM DESULFOVIBRIO DESULFURICANS ATCC 27774


Overview

The facultative sulfate/nitrate-reducing bacterium Desulfovibrio desulfuricans ATCC 27774 harbours a split-Soret cytochrome c. This cytochrome is a homodimeric protein, having two bis-histidinyl c-type haems per monomer. It has an unique architecture at the haem domain: each haem has one of the coordinating histidines provided by the other monomer, and in each monomer the haems are parallel to each other, almost in van der Waals contact. This work reports the cloning and sequencing of the gene encoding for this cytochrome and shows, by transcriptional analysis, that it is more expressed in nitrate-grown cells than in sulfate-grown ones. In addition, the gene-deduced amino acid sequence revealed two new cysteine residues that could be involved in the binding of a non-haem iron centre. Indeed, the presence of a novel type of an iron-sulfur centre (possibly of the [2Fe-2S] type) was demonstrated by EPR spectroscopy, and putative models for its localization and structure in the cytochrome molecule are proposed on the basis of the so-far-known 3D crystallographic structure of the aerobically purified split-Soret cytochrome, which lacks this centre.

About this Structure

1H21 is a Single protein structure of sequence from Desulfovibrio desulfuricans. This structure supersedes the now removed PDB entry 1ddc. Full crystallographic information is available from OCA.

Reference

A novel iron centre in the split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774., Abreu IA, Lourenco AI, Xavier AV, LeGall J, Coelho AV, Matias PM, Pinto DM, Armenia Carrondo M, Teixeira M, Saraiva LM, J Biol Inorg Chem. 2003 Feb;8(3):360-70. Epub 2002 Dec 19. PMID:12589573 Page seeded by OCA on Fri May 2 18:19:14 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h21"
Personal tools