1h2p

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1h2p.gif|left|200px]]
[[Image:1h2p.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1h2p |SIZE=350|CAPTION= <scene name='initialview01'>1h2p</scene>, resolution 2.8&Aring;
+
The line below this paragraph, containing "STRUCTURE_1h2p", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1h2p| PDB=1h2p | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h2p OCA], [http://www.ebi.ac.uk/pdbsum/1h2p PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1h2p RCSB]</span>
+
-
}}
+
'''HUMAN CD55 DOMAINS 3 & 4'''
'''HUMAN CD55 DOMAINS 3 & 4'''
Line 32: Line 29:
[[Category: Spiller, B.]]
[[Category: Spiller, B.]]
[[Category: Williams, P.]]
[[Category: Williams, P.]]
-
[[Category: alternative splicing]]
+
[[Category: Alternative splicing]]
-
[[Category: bacterial receptor]]
+
[[Category: Bacterial receptor]]
-
[[Category: complement decay accelerating factor]]
+
[[Category: Complement decay accelerating factor]]
-
[[Category: complement pathway]]
+
[[Category: Complement pathway]]
-
[[Category: enteroviral receptor]]
+
[[Category: Enteroviral receptor]]
-
[[Category: gpi-anchor]]
+
[[Category: Gpi-anchor]]
-
[[Category: ligand for cd97]]
+
[[Category: Ligand for cd97]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:21:11 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:56:32 2008''
+

Revision as of 15:21, 2 May 2008

Image:1h2p.gif

Template:STRUCTURE 1h2p

HUMAN CD55 DOMAINS 3 & 4


Overview

Decay-accelerating factor (CD55), a regulator of the alternative and classical pathways of complement activation, is expressed on all serum-exposed cells. It is used by pathogens, including many enteroviruses and uropathogenic Escherichia coli, as a receptor prior to infection. We describe the x-ray structure of a pathogen-binding fragment of human CD55 at 1.7 A resolution containing two of the three domains required for regulation of human complement. We have used mutagenesis to map biological functions onto the molecule; decay-accelerating activity maps to a single face of the molecule, whereas bacterial and viral pathogens recognize a variety of different sites on CD55.

About this Structure

1H2P is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Mapping CD55 function. The structure of two pathogen-binding domains at 1.7 A., Williams P, Chaudhry Y, Goodfellow IG, Billington J, Powell R, Spiller OB, Evans DJ, Lea S, J Biol Chem. 2003 Mar 21;278(12):10691-6. Epub 2002 Dec 22. PMID:12499389 Page seeded by OCA on Fri May 2 18:21:11 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h2p"
Personal tools