Interferon receptor

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 2: Line 2:
'''Interferon receptor''' (IFNR) is a cell surface receptor which binds interferon.<br />
'''Interferon receptor''' (IFNR) is a cell surface receptor which binds interferon.<br />
-
* '''Interferon α/β receptor''' binds interferon-α and interferon-β. It is a heterodimer with subunits INFAR1 and INFAR2. For more details see [[IFNAR]] and [[Multiple sclerosis]].<br />
+
* '''Interferon α/β receptor''' binds interferon-α and interferon-β. It is a heterodimer with subunits INFAR1 and INFAR2<ref>PMID:17969444</ref>. For more details see [[IFNAR]] and [[Multiple sclerosis]].<br />
-
* '''Interferon γ receptor''' binds interferon-γ and is a heterodimer with subunits INFGR1 and INFGR2.<br />
+
* '''Interferon γ receptor''' binds interferon-γ and is a heterodimer with subunits INFGR1 and INFGR2<ref>PMID:9462485</ref>.<br />
-
* '''Interferon δ receptor''' binds interferon-δ.
+
* '''Interferon δ receptor''' binds interferon-δ<ref>PMID:9865499</ref>.
</StructureSection>
</StructureSection>
Line 34: Line 34:
**[[3og4]], [[3og6]] – hINFDR1 extracellular domain + interleukin-29 <br />
**[[3og4]], [[3og6]] – hINFDR1 extracellular domain + interleukin-29 <br />
}}
}}
 +
== References ==
 +
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 06:41, 30 March 2016

Structure of interferon α/β receptor β chain ectodomain (green and yellow) complex with interferon-α 2 (grey and pink) and Cl- ion (green) (PDB entry 3s9d)

Drag the structure with the mouse to rotate

3D structures of interferon receptor

Updated on 30-March-2016

References

  1. Uze G, Schreiber G, Piehler J, Pellegrini S. The receptor of the type I interferon family. Curr Top Microbiol Immunol. 2007;316:71-95. PMID:17969444
  2. Pestka S, Kotenko SV, Muthukumaran G, Izotova LS, Cook JR, Garotta G. The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor. Cytokine Growth Factor Rev. 1997 Sep;8(3):189-206. PMID:9462485
  3. Lefevre F, Guillomot M, D'Andrea S, Battegay S, La Bonnardiere C. Interferon-delta: the first member of a novel type I interferon family. Biochimie. 1998 Aug-Sep;80(8-9):779-88. PMID:9865499

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

Personal tools