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Integrin

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== Structural highlights ==
== Structural highlights ==
The interactions of integrin with ligands are dependent on the presence of divalent ions<ref>PMID:10961914</ref>.
The interactions of integrin with ligands are dependent on the presence of divalent ions<ref>PMID:10961914</ref>.
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<scene name='51/516472/Cv/3'>Mg/Cl coordination site</scene>. Water molecules shown as red spheres.
</StructureSection>
</StructureSection>

Revision as of 11:42, 5 April 2016

Structure of human integrin CD11a I domain dimer complex with Mg+2 (light green) and Cl- (dark green) ions (PDB entry 1zoo)

Drag the structure with the mouse to rotate

3D structures of integrin

Updated on 05-April-2016

References

  1. ↑ Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28(4):311-39. PMID:10961914
  2. ↑ Hillis GS, MacLeod AM. Integrins and disease. Clin Sci (Lond). 1996 Dec;91(6):639-50. PMID:8976799
  3. ↑ Larjava H, Koivisto L, Heino J, Hakkinen L. Integrins in periodontal disease. Exp Cell Res. 2014 Jul 15;325(2):104-10. doi: 10.1016/j.yexcr.2014.03.010. Epub, 2014 Mar 22. PMID:24662197 doi:http://dx.doi.org/10.1016/j.yexcr.2014.03.010
  4. ↑ Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28(4):311-39. PMID:10961914

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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