Maltose-binding protein
From Proteopedia
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| - | + | <StructureSection load='1anf' size='350' side='right' caption='E. coli maltose-binding protein complex with maltose (stick model) (PDB entry [[1anf]])' scene=''> | |
| - | <StructureSection load='1anf' size='350' side='right' caption=' | + | |
== Function == | == Function == | ||
'''Maltose-binding protein''' (MBP) or '''ABC maltose transporter''' is part of the maltose/maltodextrin system in ''E. coli'' which is responsible of the catabolism of maltodextrin. MBP binds maltodextrin when the latter diffuses into the periplasm and passes it to proteins involved in active transport<ref>PMID:10452611</ref>. | '''Maltose-binding protein''' (MBP) or '''ABC maltose transporter''' is part of the maltose/maltodextrin system in ''E. coli'' which is responsible of the catabolism of maltodextrin. MBP binds maltodextrin when the latter diffuses into the periplasm and passes it to proteins involved in active transport<ref>PMID:10452611</ref>. | ||
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== Structural highlights == | == Structural highlights == | ||
| - | + | The MBP sugar binding cleft is rich with protein-ligand hydrogen bonds<ref>PMID:9309217</ref>. | |
| + | </StructureSection> | ||
==3D structures of maltose-binding protein== | ==3D structures of maltose-binding protein== | ||
Revision as of 08:35, 17 April 2016
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3D structures of maltose-binding protein
Updated on 17-April-2016
References
- ↑ Kapust RB, Waugh DS. Escherichia coli maltose-binding protein is uncommonly effective at promoting the solubility of polypeptides to which it is fused. Protein Sci. 1999 Aug;8(8):1668-74. PMID:10452611 doi:http://dx.doi.org/10.1110/ps.8.8.1668
- ↑ Sun P, Tropea JE, Waugh DS. Enhancing the solubility of recombinant proteins in Escherichia coli by using hexahistidine-tagged maltose-binding protein as a fusion partner. Methods Mol Biol. 2011;705:259-74. doi: 10.1007/978-1-61737-967-3_16. PMID:21125392 doi:http://dx.doi.org/10.1007/978-1-61737-967-3_16
- ↑ Quiocho FA, Spurlino JC, Rodseth LE. Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor. Structure. 1997 Aug 15;5(8):997-1015. PMID:9309217
