L-rhamnose isomerase
From Proteopedia
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| - | <StructureSection load='1de6' size='450' side='right' caption='Structure of L-rhamnose isomerase tetramer complex with L-rhamnitol (PDB entry [[1de6]])' scene='55/551207/Cv/ | + | <StructureSection load='1de6' size='450' side='right' caption='Structure of L-rhamnose isomerase tetramer complex with L-rhamnitol (PDB entry [[1de6]])' scene='55/551207/Cv/6' pspeed='8'> |
== Function == | == Function == | ||
'''L-rhamnose isomerase''' (LRI) catalyzes the interconversion of L-rhamnose to L-rhamnulose or D-allose to D-psicose. LRI participates in fructose and mannose metabolism<ref>PMID:15342115</ref>. | '''L-rhamnose isomerase''' (LRI) catalyzes the interconversion of L-rhamnose to L-rhamnulose or D-allose to D-psicose. LRI participates in fructose and mannose metabolism<ref>PMID:15342115</ref>. | ||
== Structural highlights == | == Structural highlights == | ||
| - | The biological assembly of LRI from ''Escherichia coli'' is <scene name='55/551207/Cv/ | + | The biological assembly of LRI from ''Escherichia coli'' is <scene name='55/551207/Cv/7'>homotetramer</scene>. The <scene name='55/551207/Cv/4'>active site</scene> of LRI contains <scene name='55/551207/Cv/5'>catalytic Zn+2 and Mn+2 ions</scene><ref>PMID:10891278</ref>. Water molecules shown as red spheres. |
</StructureSection> | </StructureSection> | ||
Revision as of 09:57, 29 June 2017
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3D structures of L-rhamnose isomerase
Updated on 29-June-2017
References
- ↑ Leang K, Takada G, Fukai Y, Morimoto K, Granstrom TB, Izumori K. Novel reactions of L-rhamnose isomerase from Pseudomonas stutzeri and its relation with D-xylose isomerase via substrate specificity. Biochim Biophys Acta. 2004 Sep 6;1674(1):68-77. PMID:15342115 doi:http://dx.doi.org/10.1016/j.bbagen.2004.06.003
- ↑ Korndorfer IP, Fessner WD, Matthews BW. The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution. J Mol Biol. 2000 Jul 21;300(4):917-33. PMID:10891278 doi:http://dx.doi.org/10.1006/jmbi.2000.3896
