Menin
From Proteopedia
(Difference between revisions)
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| - | <StructureSection load='3u86' size='340' side='right' caption='Structure of human menin complex with | + | <StructureSection load='3u86' size='340' side='right' caption='Structure of human menin (grey) complex with Jun-D peptide (green) (PDB code [[3u86]]).' scene=''> |
== Function == | == Function == | ||
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== Disease == | == Disease == | ||
Men mutations may be a common mechanism for inactivating tumor suppressor gene products in familial cancer<ref>PMID:15254225</ref>. | Men mutations may be a common mechanism for inactivating tumor suppressor gene products in familial cancer<ref>PMID:15254225</ref>. | ||
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| - | == Relevance == | ||
== Structural highlights == | == Structural highlights == | ||
| + | Jun-D interacts with Men in a deep pocket via 8 residues mainly<ref>PMID:22327296</ref>. | ||
==3D structures of menin== | ==3D structures of menin== | ||
Revision as of 09:14, 20 April 2016
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