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NADPH-Cytochrome P450 Reductase
From Proteopedia
(Difference between revisions)
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | |||
| - | *P450r | ||
| - | |||
| - | **[[2bpo]] - yP450r (mutant) - yeast<br /> | ||
| - | **[[2bf4]], [[2bn4]] - yP450r<br /> | ||
| - | **[[3es9]], [[1ja0]] - rP450r - rat<br /> | ||
| - | **[[1j9z]], [[1ja1]], [[3ojw]], [[3ojx]] - rP450r (mutant)<br / > | ||
| - | **[[3wkt]] - rP450r (mutant) + heme oxygenase 1<br /> | ||
| - | **[[3qfc]] – hP450r (mutant) - human<br /> | ||
*P450r FMN-binding domain (residues 61-241) | *P450r FMN-binding domain (residues 61-241) | ||
| - | **[[1b1c]] - hP450r <br /> | + | **[[1b1c]] - hP450r + FMN - human<br /> |
*P450r FAD/NADPH domain (residues 241-677) | *P450r FAD/NADPH domain (residues 241-677) | ||
| - | **[[3qfs]] – hP450r<br /> | + | **[[3qfs]] – hP450r + FAD + NADP<br /> |
| - | **[[3qft]] - hP450r (mutant) | + | **[[3qft]] - hP450r (mutant) + FAD + NADP<br /> |
| - | + | ||
*P450r FMN-binding and FAD/NADPH domains (residues 64-677) | *P450r FMN-binding and FAD/NADPH domains (residues 64-677) | ||
| - | **[[1amo]] - rP450r <br /> | + | **[[2bpo]] - yP450r (mutant) + FAD + FMN + NADP - yeast<br /> |
| - | **[[3qe2]] – hP450r<br /> | + | **[[2bf4]], [[2bn4]] - yP450r + FAD + FMN + NADP<br /> |
| - | **[[3qfr]] | + | **[[3es9]], [[1ja0]] - rP450r + FAD + FMN + NADP - rat<br /> |
| + | **[[1j9z]], [[1ja1]] - rP450r (mutant) + FAD + FMN + NADP<br / > | ||
| + | **[[3ojw]], [[3ojx]] - rP450r (mutant) + FAD + FMN<br / > | ||
| + | **[[3wkt]] - rP450r (mutant) + heme oxygenase 1 + FAD + FMN + NADP + heme<br /> | ||
| + | **[[1amo]] - rP450r + FAD + FMN + NADP<br /> | ||
| + | **[[3qe2]] – hP450r + FAD + FMN + NADP<br /> | ||
| + | **[[3qfc]], [[3qfr]] – hP450r (mutant) + FAD + FMN + NADP<br /> | ||
| + | **[[3fjo]] – yP450r/hP450r + FAD + FMN<br /> | ||
| + | |||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:21, 5 May 2016
NADPH-Cytochrome P450 Reductase (P450r) is the electron donor for several oxygenase enzymes including Cytochrome P450[1].
See also NADPH Cytochrome P450 Oxidoreductase.
3D Structures of NADPH-Cytochrome P450 Reductase
Updated on 05-May-2016
References
- ↑ Hamdane D, Xia C, Im SC, Zhang H, Kim JJ, Waskell L. Structure and function of an NADPH-cytochrome P450 oxidoreductase in an open conformation capable of reducing cytochrome P450. J Biol Chem. 2009 Apr 24;284(17):11374-84. Epub 2009 Jan 26. PMID:19171935 doi:10.1074/jbc.M807868200
